An improved density-based spatial clustering of applications with noise (IDBSCAN) analysis approach based on kurtosis and sample entropy (SE) is presented for the identification of operational state in order to provide accurate monitoring of spindle operation condition. This is because of the low strength of the shock signal created by bearing of precision spindle of misalignment or imbalanced load, and the difficulties in extracting shock features. Wavelet noise reduction begins by dividing the recorded vibration data into equal lengths. Features like kurtosis and entropy in the frequency domain are used to generate feature vectors that indicate the bearing operation state. IDBSCAN cluster analysis is then utilized to establish the ideal neighborhood radius (Eps) and the minimum number of objects contained within the neighborhood radius (MinPts) of the vector set, which are combined to identify the bearing operating condition features. Finally, utilizing data from the University of Cincinnati, the approach was validated and assessed, attaining a condition detection accuracy of 99.2%. As a follow-up, the spindle’s vibration characteristics were studied utilizing an unbalanced bearing’s load bench. Bearing state recognition accuracy was 98.4%, 98.4%, and 96.7%, respectively, under mild, medium, and overload circumstances, according to the results of the experimental investigation. Moreover, it shows that conditions of bearings under various unbalanced loads can be precisely monitored using the proposed method without picking up on specific sorts of failures.