Development of Saccharomyces cerevisiae Y486–based biosensor carrying both CPR-CYP3A4 and DIN7-GFP constructs for mutagenicity testing of procarcinogens
Abstract:In the world and Vietnam, a great number of toxic substances from industrial and agricultural activities, food production, and healthcare services are daily released into the environment. Many exogenous harmful substances are procarcinogens, but become carcinogens by the bioactivation of human cytochrome P450 enzymes (CYPs). Thus, development of analytical testing for rapid detection of procarcinogens plays a crucial role in food safety and environmental monitoring. This study aims to establish a biosensor bas… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.