Against the backdrop of the latest engineering and technical disciplines, cross-disciplinary fusion is a new strategy to cultivate high-level composite talents in the chemical safety field. Regulating China's severe safety production situation is crucial. As an essential source of talent, universities should promptly reconstruct the discipline system according to the new framework under the guiding spirit of Emerging Engineering Education. The innovation and application of intelligent technology have led to a technological revolution in chemistry fields. Therefore, universities should reasonably adjust and optimize the knowledge structure to address the social situations and the development needs of the industry for ensuring the safety of the entire chemical production process. This paper investigates the chemical industry safety production to innovatively present the fresh concept of "5 flows, 3 tactics, and 3 controls," with "5 flows" as the core, "3 tactics" as the focus, and "3 controls" as the goal. This concept serves as a significant reference for the reformation of the safety curriculum system.