Development of Single-step Protocols for the Separation of Naphtodianthrones from St. John�s Wort Extracts

Abstract

St. John s Wort (SJW) or Hypericum perforatum L. is a therapeutic plant highly used in pharmacology. Recent in vivo anti-cancer action of naphtodianthrones (NTs) has extended the research related to enrichment methodologies of SJW phyto-extracts. Therefore, the presented study pursuits the optimization of single-step extraction methodologies to obtain NTs-rich extracts from SJW.