Development of the Positive Emotions Program for Schizophrenia: An Intervention to Improve Pleasure and Motivation in Schizophrenia

Nguyen, Alexandra; Frobert, Laurent; McCluskey, Iannis; Golay, Philippe; Bonsack, Charles; Favrod, Jérôme

doi:10.3389/fpsyt.2016.00013

Cited by 46 publications

(34 citation statements)

References 70 publications

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“…Although some clinical studies have specifically targeted positive mental imagery (Blackwell et al ., ; Murphy et al ., ), and observed effects on behavioural activation (Renner, Ji, Pictet, Holmes, & Blackwell, ), these have not been for actual events that individuals might engage in their daily lives. Although conceptions (Nguyen et al ., ) and pilot studies (Favrod, Giuliani, Ernst, & Bonsack, ; Favrod et al ., ) of such targeted interventions have emerged, applied research is still in early stages. Introducing mental simulations to induce an anticipatory hedonic response might prove to enhance treatments such as behavioural activation; however, this is yet to be investigated.…”

Section: Discussionmentioning

confidence: 99%

Anticipatory pleasure for future experiences in schizophrenia spectrum disorders and major depression: A systematic review and meta‐analysis

Hallford

Sharma

2019

British J Clinic Psychol

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Objectives. Deficits in anticipating pleasure may be an important dimension of anhedonia and functioning in psychiatric disorders, particularly schizophrenia and depression; however, inconsistent findings have limited the conclusions that can be drawn. We conducted the first systemic review and meta-analysis of the extant literature for research comparing psychiatric groups to healthy control groups on anticipatory pleasure.Methods. Academic Search Complete, Science Direct, and CINAHL databases were systematically searched up to 9 June 2018 for relevant peer-reviewed articles, book chapters, and dissertations. Reference lists were also hand searched. A total of 36 studies were included in the review. Results.A moderate-sized deficit was observed in schizophrenia spectrum disorders (k = 32, 1,851 patients and 1,449 controls, g = À0.42 [95% CI = À0.53 to À0.31], p < .001), and a large deficit in major depression (k = 415 patients and 506 controls, g = À0.87 [95% CI = À1.23 to À0.51], p < .001), with this effect being significantly larger for depression (p < .05). Meta-regression showed that heterogeneity was partially explained in schizophrenia spectrum by longer duration of illness and lower cognitive functioning predicting larger deficits. In depression, some evidence was found that ruling out a history of psychiatric illness in controls may be related to larger effects. There was evidence for small study bias inflating estimates in schizophrenia spectrum disorders.Conclusions. Deficits in anticipatory pleasure are manifest in these disorders, and significantly more so in major depression. These findings indicate a possible therapeutic target to link cognitive, affective, and behavioural factors that precipitate and maintain disorder. Practitioner pointsAnticipatory pleasure is impaired in schizophrenia spectrum and major depression. A particular focus on enhancing anticipatory pleasure may improve motivation for rewarding behaviour and psychosocial functioning. The review contained only a small number of studies for major depression. Given the heterogeneity in effects, there are likely to be more moderators of anticipatory pleasure that require examination.

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Section: Discussionmentioning

confidence: 99%

Anticipatory pleasure for future experiences in schizophrenia spectrum disorders and major depression: A systematic review and meta‐analysis

Hallford

Sharma

2019

British J Clinic Psychol

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show abstract

“…Although some clinical studies have specifically targeted positive mental imagery (Blackwell et al, 2015;Murphy et al, 2015), and observed effects on behavioural activation (Renner et al, 2017), these have not been for actual events that individuals might engage in their daily lives. Although conceptions (Nguyen et al, 2016) and pilot studies (Favrod et al, 2010;Favrod et al, 2015) of such targeted interventions have emerged, applied research is still in early stages. Introducing mental simulations to induce an anticipatory hedonic response might prove to enhance treatments such as behavioural activation, however, this is yet to be investigated.…”

Section: Discussionmentioning

confidence: 99%

Anticipatory Pleasure for Future Experiences in Schizophrenia-Spectrum Disorders and Major Depression: A Systematic Review and Meta-Analysis

Hallford¹,

Sharma²

2019

Preprint

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Objectives: Deficits in anticipating pleasure may be an important dimension of anhedonia and functioning in psychiatric disorders, particularly schizophrenia and depression, however, inconsistent findings have limited the conclusions that can be drawn. We conducted the first systemic review and meta-analysis of the extant literature for research comparing psychiatric groups to healthy control groups on anticipatory pleasure. Methods: Academic Search Complete, Science Direct and CINAHL databases were systematically searched up to June 9th 2018 for relevant peer-reviewed articles, book chapters, and dissertations. Reference lists were also hand searched. A total of 36 studies were included in the review.Results: A moderate-sized deficit was observed in schizophrenia-spectrum disorders (k = 32, 1851 patients and 1449 controls, g = -0.42 [95%CI = -0.53-0.31], p < .001), and a large deficit in major depression (k = 415 patients and 506 controls, g = -0.87 [95%CI = -1.23-0.51], p < .001), with this effect being significantly larger for depression (p < .05). Meta-regression showed that heterogeneity was partially explained in schizophrenia-spectrum by longer duration of illness and lower cognitive functioning predicting larger deficits. In depression, some evidence was found that ruling out a history of psychiatric illness in controls may be related to larger effects. There was evidence for small study bias inflating estimates in schizophrenia-spectrum disorders. Conclusions: Deficits in anticipatory pleasure are manifest in these disorders, and significantly more so in major depression. These findings indicate a possible therapeutic target to link cognitive

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“…conceived the programme. The intervention development and the programme description have been published [27]. The French version of PEPS can be downloaded for free at www.seretablir.net/peps/.…”

Section: Methodsmentioning

confidence: 99%

“…The Positive Emotions Programme for Schizophrenia (PEPS) was developed in response to these issues [27]. PEPS is an intervention consisting of 8 one-hour sessions applied to groups of 5–10 participants.…”

Section: Introductionmentioning

confidence: 99%

Improving Pleasure and Motivation in Schizophrenia: A Randomized Controlled Clinical Trial

Favrod

Nguyen

Chaix

et al. 2019

Psychother Psychosom

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Background: Negative symptoms are frequent in patients with schizophrenia and are associated with marked impairments in social functioning. The efficacy of drug-based treatments and psychological interventions on primary negative symptoms remains limited. The Positive Emotions Programme for Schizophrenia (PEPS) is designed to improve pleasure and motivation in schizophrenia patients by targeting emotion regulation and cognitive skills relevant to apathy and anhedonia. The main hypothesis of this study is that patients who attend 8 one-hour sessions of PEPS and treatment as usual (TAU) will have lower total apathy-avolition and anhedonia-asociality composite scores on the Scale for the Assessment of Negative Symptoms (SANS) than patients who attend only TAU. Methods: Eighty participants diagnosed with schizophrenia or schizoaffective disorder were randomized to receive either TAU or PEPS + TAU. The participants were assessed by independent evaluators before randomization (T0), in a post-test after 8 weeks of treatment (T1) and at a 6-month follow-up (T2). Results: The post-test results and 6-month follow-up assessments according to an intention-to-treat analysis showed that the apathy and anhedonia composite scores on the SANS indicated statistically greater clinical improvements in PEPS participants than in non-PEPS participants. In the post-test, anhedonia but not apathy was significantly improved, thus favouring the PEPS condition. These results were sustained at the 6-month follow-up. Conclusions: PEPS is an effective intervention to reduce anhedonia in schizophrenia. PEPS is a short, easy-to-use, group-based, freely available intervention that is easy to implement in a variety of environments (ClinicalTrials.gov ID: NCT02593058).

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Development of the Positive Emotions Program for Schizophrenia: An Intervention to Improve Pleasure and Motivation in Schizophrenia

Cited by 46 publications

References 70 publications

Anticipatory pleasure for future experiences in schizophrenia spectrum disorders and major depression: A systematic review and meta‐analysis

Anticipatory pleasure for future experiences in schizophrenia spectrum disorders and major depression: A systematic review and meta‐analysis

Anticipatory Pleasure for Future Experiences in Schizophrenia-Spectrum Disorders and Major Depression: A Systematic Review and Meta-Analysis

Improving Pleasure and Motivation in Schizophrenia: A Randomized Controlled Clinical Trial

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