Development of the World Health Organization WHOQOL-BREF 
Quality of Life Assessment

Harper, Alexandra E.; Power, Michael

doi:10.1017/s0033291798006667

Cited by 5,553 publications

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“…One was a Sinhala translation of a previously validated version of the World Health Organisation Quality of life Questionnaire (WHOQOL BREF). This is a shorter version of the original WHOQOL questionnaire and consists of 26 items measuring the broad domains of physical health, psychological health, social relationships and environment (including home environment, transport, financial resources, accessibility and quality of health and social care, participation in recreational and leisure activities etc) 6 .Two other pretested questionnaires were used to collect information on the financial and psychological impact of the child's illness on the caregiver's nuclear family which included questions on caregiver's and other family member's employment status, psychological status and family income before and after the diagnosis of child's illness. Mean scores were calculated for each domain and the cut off for low, moderate and high were based on the standard deviations.…”

Section: Methodsmentioning

confidence: 99%

Quality of life of caregivers and impact on the nuclear family of children with leukaemia in the National Cancer Institute of Sri Lanka

Pathirana

Goonawardena

Wijesiriwardane

2015

J. Postgrad. Inst. Med.

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Childhood leukaemia is the commonest cancer in children aged below 15 years. A diagnosis of childhood leukaemia is a devastating experience for any parent. This hospital-based descriptive cross sectional study aimed to assess the quality of life (QOL) of caregivers and the impact on the nuclear families of children with leukaemia. A convenient sample of 140 caregivers was surveyed using an interviewer administered questionnaire. Nearly 50% of caregivers reported low QOL in the psychological 71(50.7%), social 66(47.1%) and environmental 64(45.7%) domains while most nuclear families underwent moderate financial 88(62.9%) and psychological 100(71.4%) impacts. There was a statistically significant decline in parental employment status following the diagnosis (p<0.05).

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Section: Methodsmentioning

confidence: 99%

Quality of life of caregivers and impact on the nuclear family of children with leukaemia in the National Cancer Institute of Sri Lanka

Pathirana

Goonawardena

Wijesiriwardane

2015

J. Postgrad. Inst. Med.

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“…A sum score will be used to assess overall quality of life at all assessments (T0-T2). The WHOQOL-BREF has become one of the most widely used quality of life measures in the literature [39].…”

Section: Quality Ofmentioning

confidence: 99%

Efficacy of an Online Self-Help Treatment for Comorbid Alcohol Misuse and Emotional Problems in Young Adults: Protocol for a Randomized Controlled Trial (Preprint)

Frohlich¹,

Rapinda²,

Schaub³

et al. 2018

Preprint

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Background: Alcohol misuse and emotional problems (i.e., depression and anxiety) are highly comorbid among Canadian young adults. However, there is a lack of integrated, accessible, and evidence-based treatment options for these young adults. Objective:The main goal of this study is to develop and test the efficacy of an integrated, online self-help program designed to target both alcohol misuse and emotional problems. Methods:A two-arm randomized controlled trial (RCT) design will be used to compare the efficacy of the online integrated treatment to a psychoeducational control group. A target sample of 214 participants will be recruited and randomly assigned to either condition. The integrated treatment will last 8-weeks and participants will work through 12 modules. Modules will incorporate content based on principles of Cognitive Behavioural Therapy (CBT) and Motivational Interviewing (MI). Participants in the control group will receive links to psychoeducational resources and will have access to the full treatment after follow-up. The primary outcome will be the number of Canadian standard drinks consumed in the week leading up the assessment. Secondary outcomes of interest include symptoms of depression, anxiety, alcohol-related problems, quality of life, and use of other drugs. Assessments will be completed at three time points: at baseline, at the end of treatment (i.e., 8-weeks), and at follow-up (i.e., 24-weeks). Upon completion, data will be analyzed using Generalized Linear Mixed Models (GLMM).Results: Data collection will begin in June 2018 and will continue until January 2020. Final study results will be submitted for publication by July 2020. Conclusions:Currently, there are no integrated treatments designed to target alcohol misuse and the range of emotional problems experienced in young adults. This research stands to provide an effective, accessible (i.e., online), and feasible option to treat the many struggling young adults in this country.Trial Registration: Clinicaltrials.gov ID -NCT03406039

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“…World Health Organization's Quality of Life Questionnaire 213 Items are rated on a five-point Likert scale pooled in four domains: physical health, psychological, social relationships and environment. Good psychometric data have been reported for this scale.…”

Section: Quality Of Lifementioning

confidence: 99%

Treatment of anorexia nervosa: a multimethod investigation translating experimental neuroscience into clinical practice

Schmidt

Sharpe

Bartholdy

et al. 2017

Programme Grants Appl Res

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BackgroundAnorexia nervosa (AN) is a severe psychiatric condition and evidence on how to best treat it is limited.ObjectivesThis programme consists of seven integrated work packages (WPs) and aims to develop and test disseminable and cost-effective treatments to optimise management for people with AN across all stages of illness.MethodsWP1a used surveys, focus groups and a pre–post trial to develop and evaluate a training programme for school staff on eating disorders (EDs). WP1b used a randomised controlled trial (RCT) [International Standard Randomised Controlled Trial Number (ISRCTN) 42594993] to evaluate a prevention programme for EDs in schools. WP2a evaluated an inpatient treatment for AN using case reports, interviews and a quasi-experimental trial. WP2b used a RCT (ISRCTN67720902) to evaluate two outpatient psychological therapies for AN. WP3 used a RCT (ISRCTN06149665) to evaluate an intervention for carers of inpatients with AN. WP4 used actimetry, self-report and endocrine assessment to examine physical activity (PA) in AN. WP5 conducted a RCT (ISRCTN18274621) of an e-mail-guided relapse prevention programme for inpatients with AN. WP6 analysed cohort data to examine the effects of maternal EDs on fertility and their children’s diet and growth. WP7a examined clinical case notes to explore how access to specialist ED services affects care pathways and user experiences. Finally, WP7b used data from this programme and the British Cohort Study (1970) to identify the costs of services used by people with AN and to estimate annual costs of AN for England.ResultsWP1a: a brief training programme improved knowledge, attitudes and confidence of school staff in managing EDs in school. WP1b: a teacher-delivered intervention was feasible and improved risk factors for EDs in adolescent girls. WP2a: both psychological therapies improved outcomes in outpatients with AN similarly, but patients preferred one of the treatments. WP2b: the inpatient treatment (Cognitive Remediation and Emotional Skills Training) was acceptable with perceived benefits by patients, but showed no benefits compared with treatment as usual (TAU). WP3: compared with TAU, the carer intervention improved a range of patient and carer outcomes, including carer burden and patient ED symptomatology. WP4: drive to exercise is tied to ED pathology and a desire to improve mood in AN patients. PA was not increased in these patients. WP5: compared with TAU, the e-mail-guided relapse prevention programme resulted in higher body mass index and lower distress in patients at 12 months after discharge. WP6: women with an ED had impaired fertility and their children had altered dietary and growth patterns compared with the children of women without an ED. WP7a: direct access to specialist ED services was associated with higher referral rates, lower admission rates, greater consistency of care and user satisfaction. WP7b: the annual costs of AN in England are estimated at between £45M and £230M for 2011.ConclusionsThis programme has produced evidence to inform future intervention development and has developed interventions that can be disseminated to improve outcomes for individuals with AN. Directions for future research include RCTs with longer-term outcomes and sufficient power to examine mediators and moderators of change.Trial registrationCurrent Controlled Trials ISRCTN42594993, ISRCTN67720902, ISRCTN06149665 and ISRCTN18274621.FundingThis project was funded by the National Institute for Health Research (NIHR) Programme Grants for Applied Research programme and will be published in full inProgramme Grants for Applied Research; Vol. 5, No. 16. See the NIHR Journals Library website for further project information.

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Development of the World Health Organization WHOQOL-BREF Quality of Life Assessment

Cited by 5,553 publications

References 5 publications

Quality of life of caregivers and impact on the nuclear family of children with leukaemia in the National Cancer Institute of Sri Lanka

Quality of life of caregivers and impact on the nuclear family of children with leukaemia in the National Cancer Institute of Sri Lanka

Efficacy of an Online Self-Help Treatment for Comorbid Alcohol Misuse and Emotional Problems in Young Adults: Protocol for a Randomized Controlled Trial (Preprint)

Treatment of anorexia nervosa: a multimethod investigation translating experimental neuroscience into clinical practice

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