1962
DOI: 10.1038/1931094a0
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Development of Transplantation Immunity in the Regionalized Lymph Node following Extirpation of the Original Regional Lymph Node

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1962
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Cited by 8 publications
(6 citation statements)
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“…Understanding coccolithophore physiology, and specifically coccolith formation, is of upmost importance for understanding the ecological dominance of these organisms in modern oceans ( 14 ), and interpreting the geochemical past of our planet ( 15 , 16 ). It is known that the calcium carbonate crystals that form the coccolith nucleate and grow within a specialized compartment, called the coccolith vesicle, which is located close to the center of the cell, and formation can be as fast as one per hour ( 17 ). This rapid process requires high fluxes of calcium into the coccolith vesicle.…”
mentioning
confidence: 99%
“…Understanding coccolithophore physiology, and specifically coccolith formation, is of upmost importance for understanding the ecological dominance of these organisms in modern oceans ( 14 ), and interpreting the geochemical past of our planet ( 15 , 16 ). It is known that the calcium carbonate crystals that form the coccolith nucleate and grow within a specialized compartment, called the coccolith vesicle, which is located close to the center of the cell, and formation can be as fast as one per hour ( 17 ). This rapid process requires high fluxes of calcium into the coccolith vesicle.…”
mentioning
confidence: 99%
“…Microorganisms have tremendously affected the Earth’s environment 1 2 3 4 . In particular, some species of coccolithophore phytoplankton have played a significant role in carbon fixation, which resulted in the accumulation of fossil fuels and the generation of the gas atmosphere that supports all living organisms 5 6 7 8 9 10 11 .…”
mentioning
confidence: 99%
“…Moreover, other species of coccolithophores produce crystals of calcium carbonate 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 , such as calcareous cell coverings, via biomineralization within the Golgi vesicles inside their cells 18 19 20 21 . For example, the calcite crystals of Emiliania huxleyi form a complicated structure that combines components with different crystallographic orientations; this formation is known as the V/R nucleation model 19 .…”
mentioning
confidence: 99%
“…Lymphostasis or lymphatic failure may impair regional immunity by disrupting normal immune cell trafficking leading to impaired antigen presentation and the inability of activated T cells to traffic to the primary tumor [23,24]. Support for this hypothesis is found in experimental animal and human studies documenting a delay of allogenic graft rejection when the lymphatic drainage has been compromised [25][26][27].…”
Section: Discussionmentioning
confidence: 81%