Development of visually evoked potentials in kittens: specific and nonspecific responses.

Rose, Guenter H.; Lindsley, Donald B.

doi:10.1152/jn.1968.31.4.607

Cited by 83 publications

(23 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Twelve seg ments (28.2 pm long) per cell were obtained distributed as follows: terminal (2), apical (4), oblique (4), and basilar (2) dendritic branches. Figure 1 is a dia grammatic representation of the proposed distribution on the dendritic tree of the various afferent projections according to previous studies [8,9,18,19,29], Measurements from individual animals were pool ed to obtain a mean and standard error for each age, cell area, cortical region and treatment, and were then graphed. A 3 (systems) x 3 (cortices) x 2 (conditions) x 5 (ages) multiway model I factorial analysis of variance (ANOVA) was performed [33], Diet effects on body and brain weights were assessed with the Student's t test at each developmental age.…”

Section: Dendritic Spine Analysismentioning

confidence: 99%

“…Morphological and electrophysiological studies carried out in mammals during early postnatal life have shown that the various parts of the dendritic tree of large cortical pyramidal cells receive different projections including specific and nonspecific mesence phalic and diencephalic pathways and the callosal connections [8,9,18,30], Thus, the proximal portion of the apical dendritic shaft together with parts of their basilar prolonga tions presumably both directly and indirectly receive axons belonging to the specific thala mic radiations [9,20,29,32], The upper part of the apical shaft and its terminal portion connect with the nonspecific thalamic radia tion [18,19,24], whereas the oblique branches of the apical dendrites mainly receive com missural fibers [8].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Early Undernutrition on Dendritic Spines of Cortical Pyramidal Cells in the Rat

Salas¹

1980

Dev Neurosci

View full text Add to dashboard Cite

Restricted food intake in male rats between birth and 20 days of age reduced the density of spines of layer V pyramidal cells in the frontal, parietal and occipital cortices. The loss of dendritic spines was more marked in pyramidal cell areas receiving projections from nonspecific multisynaptic systems than in cell areas associated with specific afferent systems or in areas receiving callosal projections. It was suggested that the differential effect of undernutrition in nonspecific, specific and callosal afferent projection areas of the pyramidal cortex might be related to the impairment of brain integrative functions reported to follow perinatal undernourishment.

show abstract

Section: Dendritic Spine Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of Early Undernutrition on Dendritic Spines of Cortical Pyramidal Cells in the Rat

Salas¹

1980

Dev Neurosci

View full text Add to dashboard Cite

show abstract

“…At 37 days of age (C), 21 days after the lesion, the VER's over the right and left visual cortex were not ckarly VER'S AND BEHAVIOR AFTER LESIONS 471 different. However, by this age the long-latency negative coniponent, N 2 , normally has shortened in latency and become reduced in amplitude to a point where it seems to coalesce with component N1, which by now has grown considerably in amplitude (see Rose & Lindsley, 1968). What remains of the VER at this age is a short-latency positive-negative pattern similar to that of the adult cat.…”

Section: Electrophysiological Observationsmentioning

confidence: 80%

“…If, however, PI and N1 are reflections of activity in a unitary system, i.e., the specific visual system, then unmasking of the possible contribution of the SC to the negative wave (N1) of the mature kitten VER may occur. That the equivalent of the Nt wave in the infant kitten VER is normally masked in the adult, rather than having disappeared entirely, is given some credence by observations of Rose and Lindsley (1968) which showed that reduction of the intensity of the light flash at 30 days of age will once again separate in latency the two negative waves which have appeared to coalesce under stronger light stimulation parameters.…”

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Development of visually evoked responses and visually guided behavior in kittens: Effects of superior colliculus and lateral geniculate lesions

Atwell

Lindsley

1975

Developmental Psychobiology

View full text Add to dashboard Cite

The development of visually evoked responses (VER's) and visually guided behavior was studied in kittens for 3 months after unilateral lesions of the superior colliculus (SC) or lateral geniculate nucleus (LGN) made at an early age. Of 37 kittens studied, data are presented for 6 which met 3 criteria: survival to at least 90 days of age; adequate lesion size and location; and technically satisfactory VER's and behavioral observations at appropriate intervals. The SC and LGN lesions markedly reduced or eliminated different VER components in infancy, but only the effects of LGN lesions persisted to 3 months of age. Visual field behavior deficits occurred following both types of lesions, but only those following SC lesions persisted to 3 months of age. These results are interpreted in terms of the functional status of the structures mediating the VER's and behavior at the time the lesions were made.

show abstract

A comparison of somatotopic organization in sensory neocortex of newborn kittens and adult cats

Rubel

1971

J of Comparative Neurology

View full text Add to dashboard Cite

To determine the state of functional development in the newborn kitten's somatic sensory system, the organizat Lon of mechanoreceptive projections to the sensorimotor cortex was compared to that OP the adult cat. Microelectrode mapping procedures were used.Projections from all contralateral body suyfaces to the primary somatomotor cortex (SmI) are present at birth and respond to mechanical stimulation of the receptors. The somatotopic organization of these projections in the newborn kitten is similar to that in the adult cortex with respect to the cortical region receiving projections from each part of the body and to the detailed arrangement of the projections within each of these cortical subdivisions.The relative sizes of peripheral receptive fields, and the intensity of stimulation effective for eliciting a response were similar for projections in SmT cortex of both kittens and adults. At both ages receptive field sizes decreased as their locations approached the distal portion of the limbs or rostra1 part of the face.In adults and newborns, over 75% of the neuronal responses were elicited by gentle bending of the hairs or light touch to the glabrous skin surfaces.Other similarities between adult and newborn sensorimotor cortexes included : ( a ) receptive fields of projections to SmI cortex were of fixed, local field type; ( b ) projections to SmII cortex responded to mechanical stimulation of the receptors; ( c ) ipsilateral as well as contralateral body surfaces were represented in SmII cortex; (d) the columnar arrangement of neurons and their receptive fields were apparent in the SmI cortex; (e) the coronal sulcus formed a division between the representations of the forepaw and face.Differences between newborn kittens and adult cats included: (a) shorter latency from electrical stimulation of the skin to a SmI cortical response in adults; (b) projections to SmI cortex having "disjunctive" receptive fields were not found in newborn kittens but existed in the adults; (c) the diversity of receptive field types found in neurons of the adult postcruciate MsI cortex was not found in newborn kittens; ( d ) newborn subjects displayed less variability in the somatotopic organization of projections and less overlap in the receptive fields of projections to SmI cortex.It is suggested that the SmI cortex develop as a point-to-point reflection of the distribution of mechanosensitive receptors in the body and that the complexities in this organization seen in the adult cortex occur during postnatal development .Differences between neurons in the ever, concomitant changes in the coding of neocortex of newborn kittens and adult sensory information by these neurons have cats have been demonstrated anatomically not been demonstrated. (f'urpura, '61; Voeller,Since the work of Schemer and Oeconopura, '63; Scheibel and Scheibel, '64), his-mos ('54) it has been known that when an tochemically (Himwich, Pscheidt and __- 447 EDWIN W RUBELelectric shock is applied to the forepaw of a newborn kitten. an evoked potential c...

show abstract

Development of visually evoked potentials in kittens: specific and nonspecific responses.

Cited by 83 publications

References 0 publications

Effects of Early Undernutrition on Dendritic Spines of Cortical Pyramidal Cells in the Rat

Effects of Early Undernutrition on Dendritic Spines of Cortical Pyramidal Cells in the Rat

Development of visually evoked responses and visually guided behavior in kittens: Effects of superior colliculus and lateral geniculate lesions

A comparison of somatotopic organization in sensory neocortex of newborn kittens and adult cats

Contact Info

Product

Resources

About