Climate change is a major concern. Climate change causes changes in the seasons and hydrological systems. Landslides are one of the most common hydrometeorological disasters in Indonesia. This study identifies indicators of economic and social vulnerability to the risk of landslides in the Tawangmangu and Kejajar sub-districts. The method used is scoring and weighting of each economic indicator namely the Gross Domestic Regional Product at Current Prices (PDRB ADHB) of the sub-district and the number of poor people, as well as social indicators used, including population growth rate, sex ratio, population density data, the number of children at risk, the number of elderly at risk which are analyzed using the SoVI index referring to the Regulation of the National Disaster Management Agency No. 2 Year 2012 and research conducted by Sulma, 2012 to determine the vulnerability of the two sub-districts to landslides. Tawangmangu and Kejajar sub-districts are classified as areas with moderate vulnerability, so the economic and social conditions of the Kejajar sub-district are more vulnerable to the risk of landslides. If a region has a high SoVI index due to landslides, it can affect agricultural productivity because landslides affect agricultural land. The government can use disaster studies as a basis for determining broader regional policies and accelerating regional economic recovery through the improvement of economic facilities and infrastructure in disaster-prone production sectors.