2000
DOI: 10.1002/1526-968x(200011/12)28:3/4<125::aid-gene50>3.0.co;2-s
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Developmental effects of a chimericultraspiracle gene derived fromDrosophila andChironomus

Abstract: The ultraspiracle (usp) gene encodes a nuclear receptor that forms a heterodimer with the ecdysone receptor (EcR) to mediate transcriptional responses to the insect steroid hormone, 20-hydroxyecdysone (20HE). The responses ultimately elicit changes associated with molting and metamorphosis. Although Ultraspiracle (USP) is required at several developmental times, it is unclear whether USP plays stage-specific roles in Drosophila. A chimeric transgene (d/cusp), produced by replacing the ligand-binding domain (LB… Show more

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Cited by 18 publications
(1 citation statement)
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“…Formation of larva-like, uncontracted puparium has also been known in mutants in which hormonal induction of metamorphosis is compromised (e.g. [18]). The result of mosaic obst-E RNAi experiments rule out the possibility that obst-E regulates the shape of the puparium through systemic effect on metamorphosis.…”
Section: Discussionmentioning
confidence: 99%
“…Formation of larva-like, uncontracted puparium has also been known in mutants in which hormonal induction of metamorphosis is compromised (e.g. [18]). The result of mosaic obst-E RNAi experiments rule out the possibility that obst-E regulates the shape of the puparium through systemic effect on metamorphosis.…”
Section: Discussionmentioning
confidence: 99%