Developmental pathways to autism: A review of prospective studies of infants at risk

Jones, Emily J. H.; Gliga, Teodora; Bedford, Rachael; Charman, Tony; Johnson, Mark H.

doi:10.1016/j.neubiorev.2013.12.001

Cited by 516 publications

(456 citation statements)

References 255 publications

(319 reference statements)

Supporting

Mentioning

426

Contrasting

Unclassified

Order By: Relevance

“…3) seems to be a promising way to tackle a range of neurodevelopmental and drugrelated disorders. In ASD, early motor cognition anomalies resulting in basic motor-understanding difficulties could be one of the crucial neurocognitive markers for ASD detection (Becchio, Pierno, Mari, Lusher, & Castiello, 2007;Cattaneo et al, 2007;Fabbri-Destro et al, 2009;Parma, Bulgheroni, Tirindelli, & Castiello, 2013;Rochat et al, 2013), and potentially they could be tested even in infancy, before the onset of unequivocal behavioral symptoms (for reviews from nonmotor perspectives, see Jones, Gliga, Bedford, Charman, & Johnson, 2014;Keehn, Müller, & Townsend, 2013;Klin, Shultz, & Jones, 2015). Furthermore, considering that ASD is a lifelong condition that usually requires permanent assistance, motor cognition anomalies may assume a pivotal role for setting (early) rehabilitative protocols to improve social functioning (Pineda, Carrasco, Datko, Pillen, & Schalles, 2014;Rogers et al, 2014;Zwaigenbaum, Bryson, & Garon, 2013).…”

Section: Discussionmentioning

confidence: 99%

The motor way: Clinical implications of understanding and shaping actions with the motor system in autism and drug addiction

Casartelli

Chiamulera

2015

Cogn Affect Behav Neurosci

View full text Add to dashboard Cite

To understand others' minds is crucial for survival; however, it is quite puzzling how access to others' minds can be-to some extent-direct and not necessarily mediated by conceptual reasoning. Recent advances in neuroscience have led to hypothesize a role for motor circuits not only in controlling the elementary physical features of movement (e.g., force, direction, and amplitude), but also in understanding and shaping human behavior. The concept of Bmotor cognition^refers to these aspects, and neurophysiological, neuroimaging, and behavioral studies in human and nonhuman primates support this view. From a clinical perspective, motor cognition represents a challenge in several domains. A thorough investigation of the neural mechanisms mediating motor action/intention understanding and automatized/compulsive behaviors seems to be a promising way to tackle a range of neurodevelopmental and drug-related disorders. On the one hand, anomalies in motor cognition may have cascade effects on social functioning in individuals with autism spectrum disorder (ASD); on the other, motor cognition may help explain the pathophysiology of drug-seeking and drug-taking behaviors in the most severe phase of drug addiction (i.e., see drug dependence, motor low-order cue reactivity). This may represent a promising approach that could improve the efficacy of rehabilitative interventions. The only way to shed light on multifactorial disorders such as ASD and drug addiction is through the investigation of their multiple factors. This motor way can promote new theoretical and experimental perspectives that would help bridge the gap between the basic neuroscience approach and clinical practice.

show abstract

Section: Discussionmentioning

confidence: 99%

The motor way: Clinical implications of understanding and shaping actions with the motor system in autism and drug addiction

Casartelli

Chiamulera

2015

Cogn Affect Behav Neurosci

View full text Add to dashboard Cite

show abstract

“…Thus, conflicting results from the literature on early signs of ASD may be partially explained by differences in stimulus and task design (Falck‐Ytter, Bolte, & Gredeback, 2013; Jones, Gliga, Bedford, Charman, & Johnson, 2014). It is essential to understand how stimulus design impacts on infant social fixation in typical development in order to provide a sound basis for explorations of atypical development.…”

mentioning

confidence: 99%

Multiple Measures of Fixation on Social Content in Infancy: Evidence for a Single Social Cognitive Construct?

Gillespie‐Smith

Boardman

Murray

et al. 2015

Infancy

View full text Add to dashboard Cite

The preference of infants to fixate on social information in a stimulus is well known. We examine how this preference manifests across a series of free‐viewing tasks using different stimulus types. Participants were thirty typically developing infants. We measured eye movements when viewing isolated faces, faces alongside objects in a grid, and faces naturally presented in photographed scenes. In each task, infants fixated social content for longer than nonsocial content. Social preference scores representing distribution of fixation to social versus general image content were highly correlated and thus combined into a single composite measure, which was independent of demographic and behavioral measures. We infer that multiple eye‐tracking tasks can be used to generate a composite measure of social preference in infancy. This approach may prove useful in the early characterization of developmental disabilities.

show abstract

“…Some studies suggest that an atypical pattern of verbal development is already present in 12-monthold infants from the HR group (see Jones, Gliga, Bedford, Charman, & Johnson, 2014;Ozonoff et al, 2014). In a study by Stone et al (2007), children from the HR group aged between 12 and 23 months scored lower in tests measuring the understanding of words, phrases and use of gestures during interactions with parents.…”

Section: Introductionmentioning

confidence: 99%

“…The project aimed at measuring early communication skills, such as cooing, laughing and pronouncing consonants. Characteristics associated with ASD can be already visible in early communication behaviours, which are a basis for the development of more complicated language skills (Jones et al, 2014). However, differences in communication skills between HR and low-risk (LR) groups amongst children younger than 18 months, and especially younger than 12 months, have not been conclusively confirmed.…”

Section: Introductionmentioning

confidence: 99%

Language abilities in preschool-aged siblings of children with autism spectrum disorders – preliminary report

Pisula¹,

Ziegart-Sadowska²,

Kawa³

2015

Health Psychology Report

View full text Add to dashboard Cite

Background The characteristics of autism spectrum disorders (ASD) observed among relatives of people affected with autism are referred to as broader autism phenotype (BAP). Among the components of BAP are language and communication skills. Research to date on these skills amongst the relatives of individuals with ASD is inconclusive. Furthermore, limited data are available about preschool-aged siblings of children with ASD. Participants and procedure Eighty-six children aged 4 years and 6 months – 6 years and 11 months took part in the study (32 girls and 54 boys). They were divided into four groups: siblings of children with autism (S/ASD), high-functioning children diagnosed with autism spectrum disorders (HF/ASD), siblings of children with Down syndrome (S/DS) and siblings of typically developing children (Controls, C). Communication and language skills were tested using the Vocabulary Test for Children (TSD). It was used to assess two kinds of verbal skills: receptive language (passive) and expressive language (active). Results No differences were observed in expressive lanquage or receptive language between siblings of children with ASD and siblings of children with DS as well as typically developing children. In terms of receptive language and general communication skills, siblings of children with ASD scored higher than high functioning children with ASD. High functioning children with ASD displayed difficulties with receptive language, expressive language, general language and communication skills. Conclusions The results suggest that siblings of children with ASD do not display deficits in communication and language skills. It is however important to note that due to a small sample size this study should be considered as preliminary.

show abstract

Developmental pathways to autism: A review of prospective studies of infants at risk

Cited by 516 publications

References 255 publications

The motor way: Clinical implications of understanding and shaping actions with the motor system in autism and drug addiction

The motor way: Clinical implications of understanding and shaping actions with the motor system in autism and drug addiction

Multiple Measures of Fixation on Social Content in Infancy: Evidence for a Single Social Cognitive Construct?

Language abilities in preschool-aged siblings of children with autism spectrum disorders – preliminary report

Contact Info

Product

Resources

About