Device Integration Concepts in Laboratory Automation

Wolf, Alfred A.; Galambos, Péter; Széll, Károly

doi:10.1109/ines49302.2020.9147171

Cited by 8 publications

(8 citation statements)

References 10 publications

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“…An example is the HPLC method itself, which is carried out by the HPLC system. On this level, the control is implemented by the device controller, which runs on the built-in or stand-alone dedicated computer [29].…”

Section: Hierarchical Decomposition Of Automated Laboratory Processesmentioning

confidence: 99%

Towards Robotic Laboratory Automation Plug & Play: Teaching-free Robot Integration with the LAPP Digital Twin

Wolf¹,

Romeder-Finger²,

Széll³

et al. 2022

Preprint

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The Laboratory Automation Plug & Play (LAPP) framework is a high-level abstraction layer that makes the autonomous operation of life science laboratory robots possible. The plug & play nature lies in the fact that the manual teaching and configuration of robots is not required. A digital twin (DT) based concept is proposed that outlines the types of information that has to be provided for each relevant component of the system. In particular, for the devices that the robot interfaces with, the robot positions have to be defined beforehand in a device-attached coordinate system (CS) by the vendor. This CS has to be detectable by the vision system of the robot by means of optical markers placed on the front side of the device. With that, the robot is capable of tending the machine by performing the pick-and-place type transportation of standard sample carriers. This basic use case is the primary scope of the LAPP-DT framework. The hardware scope is limited to simple benchtop and mobile manipulators with parallel grippers at this stage. This paper first provides an overview of relevant literature and state-of-the-art solutions, after which it outlines the framework on the conceptual level, followed by the specification of the relevant DT parameters for the robot, for the devices and for the facility. Finally, appropriate technologies and strategies are identified for the implementation.

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Section: Hierarchical Decomposition Of Automated Laboratory Processesmentioning

confidence: 99%

Towards Robotic Laboratory Automation Plug & Play: Teaching-free Robot Integration with the LAPP Digital Twin

Wolf¹,

Romeder-Finger²,

Széll³

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…To get an overview of some of the building blocks of modern digitalized ("smart") industrial production systems, the different levels and layers of planning, control, supervision and data collection are considered. In this regard, many similarities and analogies can be drawn between industrial production and laboratories 6 . On the highest level, some type of Enterprise Resource Planning (ERP) has to take place, while underneath a Distributed Control System (DCS) or a Supervisory Control and Data Acquisition system (SCADA) resides.…”

Section: Industry Agnostic Evolution Of Automation Systemsmentioning

confidence: 99%

“…Apart from BPMN, another layer of business process automation can also be utilized in laboratory automation: RPA approaches can be used to interface with equipment that do not have APIs 6 . Automated interaction with a device software's User Interface (UI) can be achieved by RPA scripts.…”

Section: Instrument Communication and Control Approachesmentioning

confidence: 99%

“…To counter these effects, the pharmaceutical industry is starting to utilize cutting-edge digital, automation and robotic technologies being used in other sectors. As such, the mechanical and machine-manufacturing industries have traditionally been one of the first application fields to 1 Baxter AG, a Takeda company 2 Doctoral School of Applied Informatics and Applied Mathematics, Óbuda University 3 Takeda Pharmaceuticals International AG, a Takeda company 4 Baxalta Innovations GmbH, a Takeda company 5 Antal Bejczy Center for Intelligent Robotics, Óbuda University 6 Alba Regia Technical Faculty, Óbuda University, H-8000 Sz ékesfeh érv ár, Hungary Corresponding author: Ád ám Wolf, Baxalta Innovations GmbH, Takeda Pharmaceuticals, Industriestraße 67. AT-1221 Wien Email: adam.wolf@takeda.com utilize industrial revolutions.…”

Section: Introductionmentioning

confidence: 99%

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Towards Robotic Laboratory Automation Plug & Play: The "LAPP" Framework

Wolf,

Wolton,

Trapl

et al. 2021

Preprint

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Increasing the level of automation in pharmaceutical laboratories and production facilities plays a crucial role in delivering medicine to patients. However, the particular requirements of this field make it challenging to adapt cutting-edge technologies present in other industries. This article provides an overview of relevant approaches and how they can be utilized in the pharmaceutical industry, especially in development laboratories. Recent advancements include the application of flexible mobile manipulators capable of handling complex tasks. However, integrating devices from many different vendors into an end-to-end automation system is complicated due to the diversity of protocols. Therefore, various approaches for standardization have been considered, and a concept has been proposed for taking them a step further. This concept enables a mobile manipulator with a vision system to "learn" the pose of each device and -utilizing a barcode -fetch interface information from a universal cloud database. This information includes control and communication protocol definitions and a representation of robot actions needed to operate the device. In order to define the movements in relation to the device, devices have to feature -besides the barcode -a fiducial marker as standard. The concept will be elaborated following appropriate research activities in follow-up papers.

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“…The above-mentioned technologies were tested in the context of an ongoing research project, the subject of which revolves around studying the usability of various new technologies in laboratory automation [27,28]. Laboratory automation as a field of research addresses technologies, the aim of which is to automate the processes in various research and development laboratories in life sciences, ranging from the academia through healthcare to pharmaceutical companies.…”

Section: Surveying In Laboratory Automationmentioning

confidence: 99%

A Benchmark of Popular Indoor 3D Reconstruction Technologies: Comparison of ARCore and RTAB-Map

et al. 2020

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The fast evolution in computational and sensor technologies brings previously niche solutions to a wider userbase. As such, 3D reconstruction technologies are reaching new use-cases in scientific and everyday areas where they were not present before. Cost-effective and easy-to-use solutions include camera-based 3D scanning techniques, such as photogrammetry. This paper provides an overview of the available solutions and discusses in detail the depth-image based Real-time Appearance-based Mapping (RTAB-Map) technique as well as a smartphone-based solution that utilises ARCore, the Augmented Reality (AR) framework of Google. To qualitatively compare the two 3D reconstruction technologies, a simple length measurement-based method was applied with a purpose-designed reference object. The captured data were then analysed by a processing algorithm. In addition to the experimental results, specific case studies are briefly discussed, evaluating the applicability based on the capabilities of the technologies. As such, the paper presents the use-case of interior surveying in an automated laboratory as well as an example for using the discussed techniques for landmark surveying. The major findings are that point clouds created with these technologies provide a direction- and shape-accurate model, but those contain mesh continuity errors, and the estimated scale factor has a large standard deviation.

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Device Integration Concepts in Laboratory Automation

Cited by 8 publications

References 10 publications

Towards Robotic Laboratory Automation Plug & Play: Teaching-free Robot Integration with the LAPP Digital Twin

Towards Robotic Laboratory Automation Plug & Play: Teaching-free Robot Integration with the LAPP Digital Twin

Towards Robotic Laboratory Automation Plug & Play: The "LAPP" Framework

A Benchmark of Popular Indoor 3D Reconstruction Technologies: Comparison of ARCore and RTAB-Map

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