In the hydrological cycle, runoff precipitation is one of the most significant and complex phenomena. In order to develop and improve predictive models, different perspectives have been presented in its modeling. Hydrological processes can be confidently modeled with the help of artificial intelligence techniques. In this study, the runoff of the Leilanchai watershed was simulated using artificial neural networks (ANNs) and M5 model tree methods and their hybrid with wavelet transform. Seventy percent of the data used in the train state and thirty percent in the test state were collected in this watershed from 2000 to 2021. In addition to daily and monthly scales, simulated and observed results were compared within each scale. Initially, the rainfall and runoff time series were divided into multiple sub-series using the wavelet transform to combat instability. The resultant subheadings were then utilized as input for an ANN and M5 model tree. The results demonstrated that hybrid models with wavelet improved the ANN model's daily accuracy by 4% and its monthly accuracy by 26%. It also improved the M5 model tree's daily and monthly accuracy by 4% and 41%. The wavelet-M5 model's accuracy does not diminish to the same degree as the wavelet-ANN (WANN) model as the forecast horizon lengthens. Consequently, the Leilanchai watershed has a relatively stable behavior pattern. Finally, hybrid models, in conjunction with the wavelet transform, improve forecast accuracy.