Dexmedetomidine as an adjuvant to bupivacaine in ultrasound-guided serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries

Menshawi, Mohammed Abdelsalam; Fahim, Hany Magdy

doi:10.1186/s42077-021-00171-5

Cited by 2 publications

(1 citation statement)

References 44 publications

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“…From the perspective of increasing trends in the current research on nerve block, the injection of dexmedetomidine around the nerve has recently become the focus of many studies. In other words, dexmedetomidine (13,25,26) has become a new target drug for nerve block in recent years. In terms of postoperative pain management, adductor canal block and local in ltration analgesia may be a good method for postoperative analgesia in lower extremity surgery.…”

Section: Abstract and Research Trendsmentioning

confidence: 99%

The global publication trend and research development of nerve block: A visualisation analysis between 1997 and 2021

Dong

Zhao

et al. 2022

Preprint

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Background: Nerve block is a clinical technique for relieving pain during surgery as well as for postoperative analgesia and chronic pain. Here, we analysed the trends in nerve block research and compared the contributions from different countries, institutions, journals, and authors. Methods: We extracted all studies concerning nerve block published between 1997 and 2021 from the Web of Science database. Microsoft Excel and VOSviewer were used to collect publication data, analyse publication trends, and visualize relevant results. Results: A total of 6,437 publications with 111,612 citations were identified between 1997 and 2021. The United States contributed the greatest number of publications (2010), whereas China ranked second (518). Regional Anesthesia & Pain Medicine had published the most papers concerning nerve block. Harvard University and Mariano ER were the most productive institution and author, respectively, in the field. Keywords were categorized into five clusters: the association between nerve block and anaesthesia or analgesia, local anaesthetic drugs for nerve block, nerve block techniques, nerve block for postoperative analgesia, and nerve block for oral local anaesthesia. Management-related research was a heavily researched topic in the field. Conclusions: We concluded that the United States contributed the most studies, and developing countries, led by China, are also encouraging study in this area. The exploration of new drugs in the fields of nerve block, multi-modal analgesia after surgery, treatment of chronic pain, analgesia for thoracic and abdominal surgeries, and analgesic interventions in oral therapy are a potential focus for future research.

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Section: Abstract and Research Trendsmentioning

confidence: 99%

The global publication trend and research development of nerve block: A visualisation analysis between 1997 and 2021

Dong

Zhao

et al. 2022

Preprint

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Ropivacaine versus ropivacaine plus dexmedetomidine in serratus anterior plane block patients undergoing post-thoracotomy surgery: a randomized, double-blinded clinical trial

Rashidi,

Mahmoodi,

Baghbanian

et al. 2024

BMC Anesthesiol

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Background This study was designed and implemented to investigate the addition of dexmedetomidine to Serratus Anterior Plane Block (SAP) with ropivacaine in reducing pain in patients undergoing post-thoracotomy surgery. Methods This study included patients classified as American Society of Anesthesiology (ASA) Physical Status II, with a body mass index (BMI) under 40, who were undergoing thoracotomy at Imam Khomeini Hospital in Ahvaz. The subjects were randomly divided into two groups using a randomized controlled trial design. After surgery, in the recovery room, SAP was performed for patients with ropivacaine (0.4 ml/kg of 0.2% ropivacaine solution) (group R) and ropivacaine plus dexmedetomidine (0.5 μg/kg) (group RD). Pain (with verbal rating scale, VNRS), blood pressure (systolic, diastolic, and mean arterial pressure (MAP)), heart rate (HR), and blood oxygen saturation (O2 sat) were measured and recorded before the intervention, and 1, 6, 12, 24, and 48 h after the intervention. Results Finally, 74 patients were included in this study. Both groups exhibited significant pain reduction at one hour, with sustained pain relief observed in the RD group at 6, 12, and 24 h ( P < 0.001). The RD group also showed having lower values HR and MAP at 6 and 12 h ( P < 0.001). Patients in the RD group received painkillers faster ( P = 0.005) and required lower total narcotic usage ( P < 0.0001). Two RD group patients experienced transient bradycardia, which resolved without treatment. Conclusion The findings of this study show that SAP block with dexmedetomidine is an effective and safe drug along with ropivacaine as a nerve-blocking agent in thoracotomy candidates.

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Dexmedetomidine as an adjuvant to bupivacaine in ultrasound-guided serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries

Cited by 2 publications

References 44 publications

The global publication trend and research development of nerve block: A visualisation analysis between 1997 and 2021

The global publication trend and research development of nerve block: A visualisation analysis between 1997 and 2021

Ropivacaine versus ropivacaine plus dexmedetomidine in serratus anterior plane block patients undergoing post-thoracotomy surgery: a randomized, double-blinded clinical trial

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