Dexmedetomidine in the treatment of toxicologic conditions: a systematic review and review of the toxicology investigators consortium database

Dexmedetomidine in the emergency department: A prospective observational cohort study

“…7 DEX has also been used successfully for procedural sedation 8 and for the sedation of nonintubated patients with agitation due to intoxication and poisoning. 9,10 The emergency department (ED) is a care domain in which DEX could be effectively used to improve outcome, yet the use of DEX in the ED is uncommon and understudied. 11 Barriers to the use of DEX in the ED have not been systematically studied but may include unfamiliarity, lack of high-quality data to support use, hospital policies limiting DEX use, and the slow onset of action of DEX.…”

“…The use of DEX in patients treated with noninvasive positive pressure ventilation (NIPPV) is associated with reductions in delirium incidence and need for intubation 7 . DEX has also been used successfully for procedural sedation 8 and for the sedation of nonintubated patients with agitation due to intoxication and poisoning 9,10 …”