Dexmedetomidine sedation combined with epidural anesthesia for laparoscopy in a patient with suspected tuberculosis

Kang, Yanming; Ni, Juan; Wu, Lan

doi:10.1097/md.0000000000012144

Medicine

2018

DOI: 10.1097/md.0000000000012144

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Dexmedetomidine sedation combined with epidural anesthesia for laparoscopy in a patient with suspected tuberculosis

Yanming Kang

Juan Ni

Lan Wu

Abstract: We conclude that administration of dexmedetomidine combined with epidural anesthesia can provide comfortable sedation for short laparoscopic procedures in patients with suspected tuberculosis. This technique can minimize the risk of nosocomial infection.

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Cited by 4 publications

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“…Dexmedetomidine is a new alpha (α) 2-adrenergic agonist with good anesthetic effects. Research has reported a stable patient condition without increased risks of adverse events such as respiratory depression after the administration of dexmedetomidine [5] . To this end, this study was undertaken to evaluate the effect of dexmedetomidine on patient recovery from anesthesia in gynecologic laparoscopic surgery.…”

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Effect of Dexmedetomidine on Recovery from Anesthesia in Gynecologic Laparoscopic Surgery

Niu¹,

Xu²,

Huang³

2023

IJPS

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To evaluate the effect of dexmedetomidine on patient recovery from anesthesia in gynecologic laparoscopic surgery. A total of 74 patients who underwent gynecological laparoscopic surgery in our hospital between January 2020 and March 2022 were recruited and assigned via random method to receive either 0.6 μg/ kg of saline (observation group) or 0.6 μg/kg of dexmedetomidine (experimental group) before anesthesia induction during gynecologic laparoscopic surgery, with 37 cases in each group. Outcome measures included postoperative indices (recovery time, awakening time, orientation recovery time and extubation time), Ramsay scores, hemodynamic indices (heart rate, mean arterial pressure, pulse oximetry) at different time points and postoperative adverse events. Dexmedetomidine resulted in significantly shorter respiratory recovery time, awakening time, orientation recovery time and extubation time vs. control treatment (p<0.05). The Ramsay scores in the experimental group were significantly higher than those in the observation group (p<0.05) after treatment. Patients receiving dexmedetomidine showed lower heart rate and mean arterial pressure levels and higher pulse oximetry levels at extubation and 15 min after extubation than the controls (p<0.05). The incidence of postoperative adverse reactions in the experimental group was significantly lower than that in the observation group (p<0.05). Dexmedetomidine effectively shortens the recovery time of respiration, awakening time, recovery time of orientation and extubation time in patients undergoing gynecological laparoscopy and maintains the hemodynamic stability of the body without increasing the risk of postoperative adverse events in patients.

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confidence: 99%

Effect of Dexmedetomidine on Recovery from Anesthesia in Gynecologic Laparoscopic Surgery

Niu¹,

Xu²,

Huang³

2023

IJPS

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Dexmedetomidine

2018

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Anesthetic Management of a Patient With Catecholaminergic Polymorphic Ventricular Tachycardia

Shionoya

Hirayama

Saito

et al. 2022

Anesthesia Progress

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Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare inherited arrhythmogenic disorder induced by adrenergic stress. Electrophysiologically, it is characterized by emotional stress- or exercise-induced bidirectional ventricular tachycardia that may result in cardiac arrest. Minimizing perioperative stress is critical as it can reduce fatal arrhythmias in patients with CPVT. Dexmedetomidine (DEX), a centrally acting sympatholytic anesthetic agent, was used in the successful intravenous (IV) moderate sedation of a 27-year-old female patient with CPVT, a history of cardiac events, and significant dental fear and anxiety scheduled to undergo mandibular left third molar extraction. Oral surgery was successfully performed under DEX-based IV sedation to reduce stress, and no arrhythmias were observed. IV sedation with DEX provided a sympatholytic effect with respiratory and cardiovascular stability in this patient with CPVT who underwent oral surgery.

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Dexmedetomidine sedation combined with epidural anesthesia for laparoscopy in a patient with suspected tuberculosis

Abstract: We conclude that administration of dexmedetomidine combined with epidural anesthesia can provide comfortable sedation for short laparoscopic procedures in patients with suspected tuberculosis. This technique can minimize the risk of nosocomial infection.

Cited by 4 publications

References 9 publications

Effect of Dexmedetomidine on Recovery from Anesthesia in Gynecologic Laparoscopic Surgery

Effect of Dexmedetomidine on Recovery from Anesthesia in Gynecologic Laparoscopic Surgery

Dexmedetomidine

Anesthetic Management of a Patient With Catecholaminergic Polymorphic Ventricular Tachycardia

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