Dexmedetomidine versus granisetron for the management of postspinal shivering

Abotaleb, Usama I; Abdalla, Abdalla M; Abdelrahman, Ahmad S; Gad, Gad S.; Elsayed, Abdalla M.

doi:10.4103/1687-7934.198259

Cited by 4 publications

(5 citation statements)

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“…These findings indicate that dexmedetomidine has rapider onset but shorter duration, whereas granisetron has fewer hemodynamic alterations. 29 In the study by Abotaleb et al, 29 both drugs effectively reduced shivering, but the hemodynamic effects of dexmedetomidine were higher, consistent with the results of our study. Ameta et al 22 compared the prophylactic effects of ketamine, tramadol, and dexmedetomidine.…”

Section: Discussionsupporting

confidence: 92%

“… 19 Bajwa et al 20 demonstrated that dexmedetomidine reduces postoperative shivering. Abotaleb et al 29 compared the effects of dexmedetomidine and granisetron on the control of shivering after anesthesia. They found no significant difference in the time for the onset of shivering, severity of shivering, response rate and the need for re-administration of the drugs between the two groups.…”

Section: Discussionmentioning

confidence: 99%

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Effects of ketamine, granisetron and dexmedetomidine on postoperative shivering and hemodynamic changes after general anesthesia: a double-blind randomized clinical trial

Modir¹,

Shabani²,

Moshiri³

et al. 2023

Medical Gas Research

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Postoperative shivering is one of the most common complications of surgeries. The current research compared the effects of ketamine, granisetron, and dexmedetomidine on reducing postoperative shivering after general anesthesia. This double-blind clinical trial enrolled 148 patients (39.08 ± 5.99 years old) who had been admitted to Vali-Asr Hospital of Arak, Iran in 2019–2021. The study drugs, including dexmedetomidine, ketamine, granisetron and normal saline, were administered in corresponding groups 30 minutes before the end of surgery. The results showed that dexmedetomidine reduced mean arterial pressure and heart rate in patients. The lowest incidence of shivering was observed in the dexmedetomidine group and it increased the duration of recovery. Overall, dexmedetomidine is recommended to reduce postoperative shivering after general anesthesia, but the increase in duration of recovery should be considered.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Effects of ketamine, granisetron and dexmedetomidine on postoperative shivering and hemodynamic changes after general anesthesia: a double-blind randomized clinical trial

Modir¹,

Shabani²,

Moshiri³

et al. 2023

Medical Gas Research

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“…It lowers the shivering threshold temperature by increasing the range of temperature thereby not stimulating the thermoregulatory defence mechanism of the body. 9 Ondansetron, which is 5-HT3 antagonist, is a common anti-emetic, and can be used to prevent post spinal shivering. Reduced incidence of shivering is attributed to inhibition of 5-hydroxytryptamine-3 (5-HT3) system 10 .…”

Section: Discussionmentioning

confidence: 99%

Comparison of Dexmedetomidine and Ondansetron for Prevention of Shivering in Lower Limb Surgeries After Spinal Anaesthesia

Dodhy¹

2020

JMS

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Objective: The purpose of the study was to compare the effectiveness of dexmedetomidine and ondansetron to prevent shivering in patients undergoing lower limb surgeries after spinal anaesthesia . Methods: This randomised double-blind and placebo-control study trial was held in orthopaedic operation theatre of Lahore General Hospital, Lahore from February 2020 to June 2020. Total of 120 adult patients who underwent elective orthopaedic surgery of lower limbs after spinal anaesthesia were divided into 3 batches. In Batch S, saline was given as placebo, in Batch O ondansetron and in Batch D dexmedetomidine was administered and shivering score were assessed for 45 min. A shivering score of ? 3 was considered as primary outcome. Results: There is statistically considerable difference, in the incidence of significant shivering (grade 3 & 4), among batches, as established by one way ANOVA. The significance value is 0.004 (i.e. p=0.004). There was no significant difference statistically between batch D and batch O (p=0.878) Conclusion: The incidence of shivering in batch S was considerably higher than that of both Batch O and batch D while no significant relationship could be proved in between batch D and batch O Key words: Dexmedetomedine, Ondansetron, Shivering, Spinal Anaesthesia

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“…Dexmedetomidine, an α2 adrenergic receptor agonist, exerts its analgesic and sedative effects through its α2 receptor affinity. 10 Li, et al 11 suggested that dexmedetomidine can increase the efficacy and prolong the duration of local anesthetic blockade.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of adding Dexmedetomidine in Fascia Iliaca Compartment Block to provide analgesia for positioning femur fracture patients before spinal anesthesia

Amin

Abdalla

Soltan

2020

Al-Azhar International Medical Journal

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Dexmedetomidine versus granisetron for the management of postspinal shivering

Cited by 4 publications

References 0 publications

Effects of ketamine, granisetron and dexmedetomidine on postoperative shivering and hemodynamic changes after general anesthesia: a double-blind randomized clinical trial

Effects of ketamine, granisetron and dexmedetomidine on postoperative shivering and hemodynamic changes after general anesthesia: a double-blind randomized clinical trial

Comparison of Dexmedetomidine and Ondansetron for Prevention of Shivering in Lower Limb Surgeries After Spinal Anaesthesia

Efficacy of adding Dexmedetomidine in Fascia Iliaca Compartment Block to provide analgesia for positioning femur fracture patients before spinal anesthesia

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