2014
DOI: 10.1007/s11892-014-0491-3
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Diabetes and Depression

Abstract: Diabetes and depression occur together approximately twice as frequently as would be predicted by chance alone. Comorbid diabetes and depression are a major clinical challenge as the outcomes of both conditions are worsened by the other. Although the psychological burden of diabetes may contribute to depression, this explanation does not fully explain the relationship between these 2 conditions. Both conditions may be driven by shared underlying biological and behavioral mechanisms, such as hypothalamic-pituit… Show more

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Cited by 402 publications
(349 citation statements)
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“…To emphasize, in our study, none of participants had symptoms of hypoglycemia or acute hyperglycemia during answering the questionnaire. Moreover, depressive symptoms may be perceived as the reaction for the diagnosis of the chronic disease and the demanding treatment of diabetes requiring implementation of many lifestyle modifications [16]. In our study, the percentage of patients with previously diagnosed depressive disorder was lower than expected and Table 2.…”
Section: Discussionmentioning
confidence: 49%
“…To emphasize, in our study, none of participants had symptoms of hypoglycemia or acute hyperglycemia during answering the questionnaire. Moreover, depressive symptoms may be perceived as the reaction for the diagnosis of the chronic disease and the demanding treatment of diabetes requiring implementation of many lifestyle modifications [16]. In our study, the percentage of patients with previously diagnosed depressive disorder was lower than expected and Table 2.…”
Section: Discussionmentioning
confidence: 49%
“…Why investigate the impact of general physical activity interventions for mental disorders, and why look at online delivery? First, there is evidence that common mental disorders are associated with increased sedentary behaviour, the development of comorbid chronic physical diseases (e.g., type 2 diabetes, obesity, cardiovascular disease, chronic pain), and even premature mortality (Gan et al, 2014;Holt et al, 2014;Smith et al, 2013). Sedentary behaviour is recognised as a key modifiable risk factor contributing to the premature mortality experienced by those with serious mental disorders (De Hert et al, 2009;Scott and Happell, 2011;Vancampfort et al, 2012a).…”
Section: Contents Lists Available At Sciencedirectmentioning
confidence: 99%
“…The propensity toward an unhealthy life-style associated with depression-lack of physical activity, diets rich in saturated fats, and refined sugarsand overall non-adherence regarding the necessary selfcare behaviors that accompany a diagnosis of diabetes, leave the non-diabetic person at risk for developing this metabolic disease and the diabetic person at risk for complications and poor outcomes. 20,21 Meta-analysis that has shown depression is associated with missed medical appointments, and non-adherence to diet, exercise, medication use, glucose monitoring, and foot care, 22 while elsewhere it was reported that as depression symptom severity increased there was a dose response increase in the degree of non-adherence to these key elements of diabetic self-care. 23 Pathways involving both autonomic and HPA-axis elements along with inflammation also appear relevant.…”
Section: Mechanisms In Depression and Diabetesmentioning
confidence: 99%