Diabetes and Diseases of the Skin

Eisert, J

doi:10.1016/s0025-7125(16)33311-9

Cited by 9 publications

(2 citation statements)

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“…This is in keeping with the clinical impression of most diabetes physicians and their patients, although the pathogenetic mechanism involved is obscure, because local application of glucose to the mucous membrane or the skin does not lead to pruritus. 3 It is worth emphasizing that significant infection was a comparatively uncommon cause of pruritus vulvae in our own patients, although the low rate of isolation of Candida and other yeasts might reflect the intermittent use of antifungal agents.…”

Section: Discussionmentioning

confidence: 59%

“…I t is generally accepted that diabetes mellitus is a cause of generalized pruritus. [1][2][3] Most articles on the subject refer to the study of Greenwood, 1 who reported a prevalence of 3% of generalized pruritus in 500 patients with diabetes mellitus. More recent workers have emphasized that the association is uncommon but have not attempted to ascertain a prevalence of generalized pruritus in a comparable nondiabetic population.…”

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confidence: 99%

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Pruritus in Diabetes Mellitus: Investigation of Prevalence and Correlation With Diabetes Control

et al. 1986

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Three hundred diabetic and 100 nondiabetic hospital outpatients (both groups of comparable age and sex distribution) were assessed for the presence of generalized and localized pruritus. Pruritus vulvae was significantly more common in diabetic women (18.4%) than in controls (5.6%) and was significantly associated with poor diabetes control (mean glycosylated hemoglobin level less than 12%). Other forms of localized pruritus were equally common in diabetic and nondiabetic patients, regardless of glycosylated hemoglobin levels. Generalized pruritus was present in 14 diabetic patients, but in 5 cases the symptom was ascribed to intercurrent illness or drug administration. Thus, generalized pruritus without apparent cause was present in only 8 diabetic patients (2.7%) and was not significantly more common than in nondiabetic patients. It is doubtful if diabetes mellitus per se should be regarded as a cause of generalized or localized pruritus, other than pruritus vulvae.

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Section: Discussionmentioning

confidence: 59%

mentioning

confidence: 99%