Diabetes Management: Expectations and Limitations

Sharma, Neeta; Rao, Gundu H. R.

doi:10.4172/2155-6156.1000662

Cited by 4 publications

(3 citation statements)

References 11 publications

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“…Employing diverse lifestyle approaches might help. Regulation of metabolic parameters such blood pressure, glucose, glycated hemoglobin, lipids, and body weight including the assessment of life quality are critical in determining the level of treatment goals by lifestyle changes [ 73 ]. However, different countries have focused on DM management and its complications on the normalization of glycemic control as assessed by hemoglobin A1 or fasting blood glucose which only addresses the need of subjects who were already diabetic.…”

Section: Discussion Of Major Findingsmentioning

confidence: 99%

“…Thus, it is imperative to design programs for the early detection of altered glucose metabolism and to carry out robust approaches for the normalization of this changed state. Furthermore, through robust prevention strategies, better diagnostic tests, early risk detection, and management of the risks will help mitigate the incidence of DM and reduce or prevent events associated with end-organ failure [ 73 ].…”

Section: Discussion Of Major Findingsmentioning

confidence: 99%

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Current Advances in the Management of Diabetes Mellitus

Aloke

Egwu²,

Aja

et al. 2022

Biomedicines

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Diabetes mellitus (DM) underscores a rising epidemic orchestrating critical socio-economic burden on countries globally. Different treatment options for the management of DM are evolving rapidly because the usual methods of treatment have not completely tackled the primary causes of the disease and are laden with critical adverse effects. Thus, this narrative review explores different treatment regimens in DM management and the associated challenges. A literature search for published articles on recent advances in DM management was completed with search engines including Web of Science, Pubmed/Medline, Scopus, using keywords such as DM, management of DM, and gene therapy. Our findings indicate that substantial progress has been made in DM management with promising results using different treatment regimens, including nanotechnology, gene therapy, stem cell, medical nutrition therapy, and lifestyle modification. However, a lot of challenges have been encountered using these techniques, including their optimization to ensure optimal glycemic, lipid, and blood pressure modulation to minimize complications, improvement of patients’ compliance to lifestyle and pharmacologic interventions, safety, ethical issues, as well as an effective delivery system among others. In conclusion, lifestyle management alongside pharmacological approaches and the optimization of these techniques is critical for an effective and safe clinical treatment plan.

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Section: Discussion Of Major Findingsmentioning

confidence: 99%

Section: Discussion Of Major Findingsmentioning

confidence: 99%

Current Advances in the Management of Diabetes Mellitus

Aloke

Egwu²,

Aja

et al. 2022

Biomedicines

View full text Add to dashboard Cite

show abstract

“…Quite a powerful statement coming from the Chairman of the Nutrition Department of the Harvard School of Public Health. Roy Taylor and associates, at the University of New Castle, UK, have shown that a low-calorie diet (850 Cal diet) caused remission in 90% of trial patients, who lost 15 Kg or more, even in those who had been diabetic for six years or more [40]. Since carbohydrate is the micronutrient, that raises blood glucose levels most significantly, the greatest debate is how low in carbohydrates the diet should be.…”

Section: Discussionmentioning

confidence: 99%

Diet and Nutrition: Metabolic Diseases

Rao¹

2018

GJNFS

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You Are What You Eat; how to win and keep health with diet", was the title of a book, that nutritionist Victor Lindlahr wrote in 1920s. Since then, several nutritionists have written extensively on this topic. Over the years, scientists, clinicians, policy makers, and professional societies, have offered contradictory advice of what to eat or what not to eat, and when to eat. In view of the fact, that my interests are focused on metabolic diseases, I will start this essay with some introduction to metabolism, as it modulates the activities at molecular, cellular, organ, and total body level. In brief, metabolism is the chemical process your body uses, to transform the food you eat into the fuel, that keeps you alive and well. Diet and nutrition by and large, consists of proteins, carbohydrates, fats and a variety of micronutrients. These substance's when ingested are broken down by enzymes in our digestive system, and then carried to the cells, where they can be used as fuel. The body either uses these metabolites immediately, or stores them in the liver, body fat, and muscles for later use. A metabolic disorder occurs, when the metabolic process fails and causes body to have either too much or too little of the essential metabolites needed to stay healthy. In the ancient science of Ayurveda, the Indian Traditional Medicine, alterations in metabolism are called "doshas", meaning metabolic defects. In the holistic approach, attempts are made to keep these dos has in a perfect balance, so that the risks for various diseases are not developed. All the known metabolic diseases, such as hypertension, excess weight, endothelial dysfunction, subclinical atherosclerosis, obesity, metabolic syndrome, and type-2 diabetes, have reached epidemic proportions worldwide. In this overview, we will discuss some of the known metabolic alterations that promote the risks for developing metabolic diseases and present our views on the subject. . This work is licensed under Creative Commons Attribution 4.0 License GJNFS.MS.ID.000504.

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Platelet Dysfunction in Type-2 Diabetes Mellitus

Rao

2017

Mechanisms of Vascular Defects in Diabetes Mellitus

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Diabetes Management: Expectations and Limitations

Cited by 4 publications

References 11 publications

Current Advances in the Management of Diabetes Mellitus

Current Advances in the Management of Diabetes Mellitus

Diet and Nutrition: Metabolic Diseases

Platelet Dysfunction in Type-2 Diabetes Mellitus

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