Diabetes Mellitus and Morbidity and Mortality Risks after Coronary Artery Bypass Surgery

Risum, Ø.; Abdelnoor, Michel; Svennevig, Jan; Levorstad, K.; Gullestad, Lars; Bjørnerheim, Reidar; Simonsen, Svein; Nitter-Hauge, S

doi:10.3109/14017439609107245

Cited by 43 publications

(22 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No signi®cant sex differences were detected in the presence of diabetes mellitus in the study patients. The long-term mortality in patients with diabetes mellitus following CABG surgery has been shown to be higher than in a non-diabetic patient group [22].…”

Section: Discussionmentioning

confidence: 99%

Assessment of changes in general health status using the short-form 36 questionnaire 1 year following coronary artery bypass grafting

Lindsay¹

2000

European Journal of Cardio-Thoracic Surgery

View full text Add to dashboard Cite

Objective: The problem addressed in the study was to gain a greater understanding of the health bene®ts of coronary artery bypass grafting (CABG). The purpose of the study was to assess general health status, using the short-form (SF)-36 questionnaire, approximately 12 months following CABG, and to document any associations between pre-operative health status, level of social support, coronary artery disease (CAD) risk factors, CAD symptom severity and post-operative health status. Methods: The study was prospective and observational in design and included assessments at two time points, namely pre-operatively in a hospital outpatient department (1995±1996) and postoperatively at home (1996±1997). Two hundred and fourteen patients awaiting elective CABG were recruited a month before the expected date of operation. Pre-operative assessment included: (1), severity of symptoms; (2), CAD risk factors; (3), SF-36 questionnaire; and (4), social activities questionnaire. Post-operative assessment measured health status using the SF-36 instrument (mean, 16.4 months). Correlation and multiple linear regression analyses were used to identify factors associated with improved health status following CABG. Results: Two hundred and fourteen patients were assessed pre-operatively and underwent CABG. There was a 4.8% 30-day mortality rate, and 183 patients were followed for a mean of 16.4 months after CABG. SF-36 scores following CABG were improved across all of the eight domains (P , 0:001). A higher social network score and higher pre-operative health status were associated with improved health status. Patients with lower health levels (SF-36 scores) prior to CABG were less likely to gain improvement in health (SF-36 scores) following CABG. Lower SF-36 scores following operation were in¯uenced by the presence of diabetes mellitus, cigarette smoking, younger age, a high socio-economic deprivation category and higher alcohol intake. Many patients had uncorrected CAD risk factors at pre-operative assessment. Conclusions: The SF-36 instrument was shown to be a useful and sensitive tool to assess differences and changes in the general health status of patients before and following CABG. High levels of social support were associated with improved health status post-operatively. Lower preoperative general health status, the presence of diabetes mellitus and cigarette smoking were associated with poorer post-operative general health status. q

show abstract

Section: Discussionmentioning

confidence: 99%

Assessment of changes in general health status using the short-form 36 questionnaire 1 year following coronary artery bypass grafting

Lindsay¹

2000

European Journal of Cardio-Thoracic Surgery

View full text Add to dashboard Cite

show abstract

“…In contrast, other studies [44][45][46][47] have demonstrated a poorer prognosis among diabetics particularly after cardiac surgery. In a large retrospective analysis of patients with ankle fractures [48], diabetes was associated with increases in hospital mortality, postoperative complications, length of hospital stay and total hospital charges.…”

Section: Diabetes and Perioperative Outcomementioning

confidence: 81%

The diabetic surgical patient

Moitra

Meiler²

2006

Current Opinion in Anaesthesiology

View full text Add to dashboard Cite

According to World Health Organization projections, anesthesiologists can expect to care for more diabetic patients than ever before. Diabetes and its associated complications present unique challenges to the perioperative physician. As biomedical research continues to unravel the genetic, cellular and molecular mechanisms of this complex metabolic disease, our specialty must be prominently involved in the design and testing of innovative treatments to protect the diabetic patient from the risks of surgery and anesthesia.

show abstract

“…[16][17][18] Female gender was a contributing factor to mortality, although not reaching standard statistically signifi cant levels ( p = 0.057), but was statistically signifi cant as a risk factor for morbidity ( p = 0.04). In regard to operative factors, CPB time was signifi cantly longer for both mortality ( p < 0.001) and morbidity ( p < 0.001).…”

Section: Cardiac Surgery In Iran Hassantashmentioning

confidence: 91%

Cardiac Surgery in an Iranian Teaching Hospital: Outcome and Risk Factors

Hassantash

Mirpoor

Afrakhteh

2004

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

Cardiac surgery in Iran has been associated with different facilities, equipment and patient populations in comparison to countries from which most of the academic papers used for identification of risk factors related to outcome and subsequent establishment of risk stratification models originate from. During a 15-month period all patients admitted for adult cardiac surgery using cardiopulmonary bypass (CBP) in a university affiliated teaching hospital were enrolled in a prospective study. Appropriate statistical tests were used to analyze data for mortality and morbidity. There were 730 adults (63% male, 37% female), with age ranged from 16 to 82 (mean, 51.4 +/- 14.4). A mortality rate of 5.3% and morbidity of 14.8% (major + minor) were observed in the whole group. Factors correlated with mortality were: age (p = 0.019), emergency surgery (p < 0.0001), redo cardiac surgery (p = 0.01), left ventricular (LV) aneurysm (p < 0.001), presence of catastrophic states (p < 0.001), low ejection fraction (p = 0.04), history of hypertension (p = 0.05), the individual surgeon (p < 0.0001), and CPB duration (p < 0.0001). Factors affecting morbidity included: female gender (p = 0.04), age (p = 0.03), emergency surgery (p = 0.001), redo surgery (p = 0.008), and catastrophic states (p < 0.001). The mortality in our study group may be compared with reports presented in the literature. Factors such as age, emergency surgery, redo cardiac surgery, and catastrophic states are statistically related to both mortality and morbidity.

show abstract

Diabetes Mellitus and Morbidity and Mortality Risks after Coronary Artery Bypass Surgery

Cited by 43 publications

References 16 publications

Assessment of changes in general health status using the short-form 36 questionnaire 1 year following coronary artery bypass grafting

Assessment of changes in general health status using the short-form 36 questionnaire 1 year following coronary artery bypass grafting

The diabetic surgical patient

Cardiac Surgery in an Iranian Teaching Hospital: Outcome and Risk Factors

Contact Info

Product

Resources

About