Diabetes mellitus as a risk factor for pulmonary complications after coronary bypass surgery

Lauruschkat, A. H.; Arnrich, Bert; Albert, Alexander; Walter, Jörg A.; Amann, Berthold; Rosendahl, Ulrich; Alexander, T; Ennker, Jürgen

doi:10.1016/j.jtcvs.2007.07.066

Cited by 26 publications

(16 citation statements)

References 27 publications

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“…The impact of DM on post-operative respiratory insufficiency arises most probably both from the direct influence of DM on respiratory function and the indirect systemic pathway (21). Lauruschat et al also reported a higher incidence of pulmonary complications in diabetic patients after CABG (34). In our study, the prolonged need for mechanical ventilation due to respiratory insufficiency in diabetics may be one reason for prolonged ICU-stay.…”

Section: Discussionsupporting

confidence: 48%

The Effect of Type II Diabetes Mellitus on Early Morbidity

Kumbasar¹,

Demircin²,

Doğan³

et al. 2011

Gazi Med J

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Objective: The impact of DM on post-operative morbidity and mortality after valve surgery is less well defined and the results of the studies are controversial. This study evaluated the effects of DM on post-operative short-term morbidity after isolated mitral valve replacement. Methods: The study population included 214 consecutive patients undergoing isolated mitral valve replacement (MVR) with mechanical valves under cardiopulmonary bypass (CPB). Patients were divided into two groups; diabetics (group I, n=36) and non-diabetics (group II, n=178). The groups were compared with respect to pre-and postoperative creatinine and blood urea nitrogen (BUN) levels, post-operative cerebrovascular disorders, arrhythmia, post-operative revision due to blood loss, surgical site infection, post-opertive extubation time, intensive care unit (ICU) and in-hospital stay time, CPB and aortic cross-clamp time. Results: In the diabetic group, post-operative rate of cerebrovascular disorders (13.9% vs. 2.8%; p=0.015), intubation time (11.5±7.6 h vs. 10.4±15.9 h; p=0.001), length of ICU stay (3.5±2.9 d vs. 2.7±2.1 d; p=0.001) and in-hospital stay (14.4±8.9 d vs. 11.1±6.9 d; p=0.023), rate of surgical site infection (19.4% vs. 3.9%; p=0.003), revision requirement rate (16.7% vs. 6.2%; p=0.045) were significantly higher. DM was also identified as an independent risk factor for surgical site infection, cerebrovascular disorder, arrhythmia and requirement of revision. Conclusion: This study showed that DM not only increases short-term morbidity due to its multiple effects but is also an independent risk factor for surgical site infection, cerebrovascular disorder, arrhythmia and requirement of revision after isolated mitral valve replacement procedures.

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Section: Discussionsupporting

confidence: 48%

The Effect of Type II Diabetes Mellitus on Early Morbidity

Kumbasar¹,

Demircin²,

Doğan³

et al. 2011

Gazi Med J

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“…Some earlier studies had reported that DM was associated with a higher risk for complications in various types of surgery, such as coronary bypass 23 and bariatric surgery. 24 However, few studies have assessed DM and urological surgeries.…”

Section: Discussionmentioning

confidence: 99%

Obesity, hypertension and diabetes mellitus affect complication rate of different nephrectomy techniques

Hua

Cheng

Zu-Jun

et al. 2014

Actas Urológicas Españolas (English Edition)

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“…It is reported that older age, smoking, obesity, diabetes, chronic obstructive pulmonary disease, hypercapnia, hypoproteinemia, prolonged duration of CPB, postoperative bacteremia, postoperative endocarditis, postoperative gastrointestinal hemorrhage with or without perforation, postoperative acute kidney injury, sternal infection, postoperative cerebral vascular accident and reoperation for bleeding increased the incidence of postoperative pulmonary complications 16, 17. This study revealed that independent risk factors for postoperative pulmonary complications included older age (>65 years), preoperative congestive heart failure, low preoperative PaO 2 , prolonged cardiopulmonary bypass, intra-operative phrenic nerve injury, and postoperative acute kidney injury.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Pulmonary Complications Following Cardiac Surgery with Cardiopulmonary Bypass

Ji¹,

Mei²,

Wang³

et al. 2013

Int. J. Med. Sci.

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Background: Pulmonary complications following cardiac surgery with cardiopulmonary bypass (CPB) are often associated with significant morbidity and mortality. However, few reports have focused on evaluating intra- and post-operative independent risk factors for pulmonary complications following cardiac surgery with CPB. This study aimed to evaluate peri-operative independent risk factors for postoperative pulmonary complications through investigating and analyzing 2056 adult patients undergoing cardiac surgery with CPB.Methods: From January 2005 to December 2012, the relevant pre-, intra-, and post-operative data of adult patients undergoing cardiac surgery with CPB in the department of cardiovascular surgery of Tongji Hospital of Tongji University in Shanghai were investigated and retrospectively analyzed. The independent risk factors for pulmonary complications following cardiac surgery with CPB were obtained through descriptive analysis and then logistic regression analysis.Results: One hundred and forty-three adult patients suffered from pulmonary complications following cardiac surgery with CPB, with an incidence of 6.96%. Through descriptive analysis and then logistic regression, independent risk factors for postoperative pulmonary complications were as follows: older age (>65 years) (OR=3.31, 95%CI 1.71-7.13), preoperative congestive heart failure (OR=2.95, 95%CI 1.41-5.84), preoperative arterial oxygenation (PaO2) (OR=0.67, 95%CI 0.33-0.85), duration of CPB (OR=3.15, 95%CI 1.55-6.21), intra-operative phrenic nerve injury (OR=4.59, 95%CI 2.52-9.24), and postoperative acute kidney injury (OR=3.21, 95%CI 1.91-6.67). Postoperative pulmonary complication was not a risk factor for hospital death (OR=2.10, 95%CI 0.89-4.33).Conclusions: A variety of peri-operative factors increased the incidence of pulmonary complications following cardiac surgery with cardiopulmonary bypass.

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Diabetes mellitus as a risk factor for pulmonary complications after coronary bypass surgery

Cited by 26 publications

References 27 publications

The Effect of Type II Diabetes Mellitus on Early Morbidity

The Effect of Type II Diabetes Mellitus on Early Morbidity

Obesity, hypertension and diabetes mellitus affect complication rate of different nephrectomy techniques

Risk Factors for Pulmonary Complications Following Cardiac Surgery with Cardiopulmonary Bypass

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