Diabetes mellitus Typ 2 und Depressivität: Was ist ursächlich für was?

Wagner, G. A.; Icks, Andrea; Albers, Bernd; Abholz, Heinz-Harald

doi:10.1055/s-0031-1299009

Cited by 8 publications

(7 citation statements)

References 13 publications

(16 reference statements)

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“…Previous research showed that depression is associated with a wide range of physical diseases with the strongest association being reported with cardiovascular diseases ( 18 ), diabetes ( 9 , 10 ), COPD ( 16 ), and chronic musculoskeletal disorders ( 11 , 12 ). However, findings on the direction of the respective associations remain heterogeneous ( 25 – 28 ).…”

Section: Introductionmentioning

confidence: 99%

The Association between Depressive Symptoms and Physical Diseases in Switzerland: A Cross-Sectional General Population Study

Rodic

Meyer

Meinlschmidt

2015

Front. Public Health

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Objective: To estimate the association between depressive symptoms and physical diseases in Switzerland, as respective findings might inform about future estimates of mental and physical health care costs.Methods: A population-based study, using data from the Swiss Health Survey collected by computer-assisted telephone interviews and additional written questionnaires during the year 2007 (n = 18,760) in Switzerland. The multistage stratified random sample included subjects aged 15 years and older, living in a private Swiss household with a telephone connection. Complete data were available for 14,348 subjects (51% of all subjects reached by telephone). Logistic regression analyses were used to estimate the associations between depressive symptoms and any physical disease, or a specific physical disease out of 13 non-communicable physical diseases assessed with a self-report checklist on common physical diseases. Analyses were adjusted for sex, age, education, occupation, and household income.Results: In the adjusted models, depressive symptoms were associated with arthrosis and arthritis [Odds Ratio (OR) = 1.79, 95% confidence interval (CI) = 1.28-2.50] and any physical disease (OR = 1.67, 95% CI = 1.33-2.10) after controlling for multiple testing.Conclusion: Our findings contribute to a better understanding of the comorbidity of depressive symptoms and arthrosis and arthritis in Switzerland and might have implications for more precise future estimates of mental and physical health care costs.

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Section: Introductionmentioning

confidence: 99%

The Association between Depressive Symptoms and Physical Diseases in Switzerland: A Cross-Sectional General Population Study

Rodic

Meyer

Meinlschmidt

2015

Front. Public Health

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“…[7], [8]; for overview: [9], [10]). Comorbid depression is consistently related to diabetes complications (diabetic retinopathy, nephropathy, neuropathy, macrovascular complications, and sexual dysfunction) [11] and also to treatment nonadherence [12].…”

Section: Introductionmentioning

confidence: 99%

Associations between Depression and Diabetes in the Community: Do Symptom Dimensions Matter? Results from the Gutenberg Health Study

et al. 2014

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ObjectivesWhile a bidirectional relationship between diabetes and depression has been established, there is little knowledge if the associations are due to somatic-affective or cognitive-affective dimensions of depression.Research Design and MethodsIn a population-based, representative survey of 15.010 participants we therefore studied the associations of the two dimensions of depression with diabetes and health care utilization among depressed and diabetic participants. Depression was assessed by the Patient Health Questionnaire PHQ-9.ResultsWe found a linear and consistent association between the intensity of depression and the presence of diabetes increasing from 6.9% in no or minimal depression to 7.6% in mild, 9% in moderate and 10.5% in severe depression. There was a strong positive association between somatic-affective symptoms but not with cognitive-affective symptoms and diabetes. Depression and diabetes were both independently related to somatic health care utilisation.ConclusionsDiabetes and depression are associated, and the association is primarily driven by the somatic-affective component of depression. The main limitation of our study pertains to the cross-sectional data acquisition. Further longitudinal work on the relationship of obesity and diabetes should differentiate the somatic and the cognitive symptoms of depression.

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“…From previous experience with a similar review [ 16 – 18 ], we expect studies to be too heterogeneous to allow for a quantitative summary of results. If, however, we find subsets of studies to be homogeneous enough, we will perform meta-analyses for incidence rates by Poisson generalized linear mixed models (GLMM) as recommended by Trikalinos et al [ 19 ].…”

Section: Methods and Designmentioning

confidence: 99%

Incidence of lower extremity amputation in the diabetic compared to the non-diabetic population: a systematic review protocol

et al. 2015

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BackgroundDiabetic individuals have a largely increased risk of lower extremity amputation (LEA) compared with non-diabetic patients. Prior systematic reviews of incidence of LEA have some limitations with respect to lack of consensus in the definition of LEA, level of LEA (all, major, minor), and definition of source population (general population or population with diabetes at risk). The purpose of our review is to evaluate the incidence of LEA in the diabetic population and its differences with regard to sex, ethnicity, age, and regions; to compare the incidence rate (IR) in the diabetic and non-diabetic population; and to investigate time trends.Methods/designWe will perform a systematic literature search in MEDLINE, Embase, Web of Knowledge, and publisher databases such as Journals@OVID and ScienceDirect. We will develop comprehensive systematic search strategies according to established guidelines for meta-analyses of observational studies in epidemiology (the MOOSE group). Two authors will independently screen abstracts and full text of all references on the basis of inclusion criteria with respect to types of study, types of population, and the main outcome. We will exclude studies if they report solely incidences of LEA among persons with diabetes mellitus when referring to the total population (diabetic and non-diabetic) and not exclusively to the diabetic population. Data extraction and assessment of risk of bias will be undertaken by two review authors working independently. We will assess incidence rate (IR) or cumulative incidence (CumI), relative risk of amputations comparing the diabetic to non-diabetic populations, cause of LEA, and type of diabetes. If we find subsets of studies to be homogeneous enough, we will perform meta-analyses for incidence rates by Poisson generalized linear mixed models (GLMM).Systematic review registrationPROSPERO CRD42015017809Electronic supplementary materialThe online version of this article (doi:10.1186/s13643-015-0064-9) contains supplementary material, which is available to authorized users.

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Diabetes mellitus Typ 2 und Depressivität: Was ist ursächlich für was?

Abstract: Knowing about this - even causal - co-morbidity is important in care, including a routine diagnostic approach to find out if the other disease is also present.

Cited by 8 publications

References 13 publications

The Association between Depressive Symptoms and Physical Diseases in Switzerland: A Cross-Sectional General Population Study

The Association between Depressive Symptoms and Physical Diseases in Switzerland: A Cross-Sectional General Population Study

Associations between Depression and Diabetes in the Community: Do Symptom Dimensions Matter? Results from the Gutenberg Health Study

Incidence of lower extremity amputation in the diabetic compared to the non-diabetic population: a systematic review protocol

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