Diabetic Foot Disorders: A Clinical Practice Guideline (2006 Revision)

Frykberg, Robert G.; Zgonis, Thomas; Armstrong, David G.; Driver, Vickie R.; Giurini, John M.; Kravitz, Steven R.; Landsman, Adam; Lavery, Lawrence A.; Moore, John C.; Schuberth, John M.; Wukich, Dane K.; Andersen, Charles A.; Vanore, John V.

doi:10.1016/s1067-2516(07)60001-5

Cited by 783 publications

(738 citation statements)

References 435 publications

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“…sensory neuropathy, vascular insufficiency, immunopathy and metabolic perturbations) can predispose these patients to infections [5,6]. SSTIs are more common and more severe in diabetic than in non-diabetic patients and constitute a leading cause of hospitalisation [7]. The risk of SSTI-related hospitalisation is more than twice as high in diabetic than in non-diabetic patients [8].…”

Section: Introductionmentioning

confidence: 99%

“…Diabetes is independently associated with increased emergency department visits for SSTIs [9], longer hospital stays [8] and infection-attributable death [10,11]. The rising prevalence of diabetes [7,12] is likely to cause increasing numbers of diabetes-related SSTIs in hospitalised patients.…”

Section: Introductionmentioning

confidence: 99%

“…SSTIs occur at all anatomic sites, but the foot is most frequently affected in diabetic patients [7]. In the USA, about 111,000 persons with diabetes are hospitalised annually with foot infections and these precede and contribute to almost 60% of all lower extremity amputations [13].…”

Section: Introductionmentioning

confidence: 99%

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Skin and soft tissue infections in hospitalised patients with diabetes: culture isolates and risk factors associated with mortality, length of stay and cost

Tabak²,

et al. 2010

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Aims/hypothesis Skin and soft tissue infections (SSTIs) cause substantial morbidity in persons with diabetes. There are few data on pathogens or risk factors associated with important outcomes in diabetic patients hospitalised with SSTIs. Methods Using a clinical research database from CareFusion, we identified 3,030 hospitalised diabetic patients with positive culture isolates and a diagnosis of SSTI in 97 US hospitals between 2003 and 2007. We classified the culture isolates and analysed their association with the anatomic location of infection, mortality, length of stay and hospital costs. Results The only culture isolate with a significantly increased prevalence was methicillin-resistant Staphylococcus aureus (MRSA); prevalence for infection of the foot was increased from 11.6 to 21.9% (p<0.0001) and for non-foot locations from 14.0% to 24.6% (p=0.006). Patients with non-foot (vs foot) infections were more severely ill at presentation and had higher mortality rates (2.2% vs 1.0%, p<0.05). Significant independent risk factors associated with higher mortality rates included having a polymicrobial culture with Pseudomonas aeruginosa (OR 3

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Skin and soft tissue infections in hospitalised patients with diabetes: culture isolates and risk factors associated with mortality, length of stay and cost

Tabak²,

et al. 2010

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“…7 Bjarnsholt T and et al said that pseudomonas plays the important role in diabetic foot infection. 8 George et al stated that diabetes accounts for up to 50 per cent of non-traumatic leg amputations.…”

Section: Discussionmentioning

confidence: 99%

Early debridement and skin grafting in diabetic ulcer to reduce morbidity.

Bora

Shahapurkar

2014

Int J of Biomed & Adv Res

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“…It was also found that among nail infected participants (n =73), 50.7% visit a doctor for their nail infection and out of this, 68.4% of them were treating the infected nail with prescribed medicine. 45 out of the 73 participants having nail infection revealed neglecting their treatment follow-up suggesting that these participants were unaware of the consequence of the nail infection if left untreated over a long period which may lead to complications ranging from gangrene to amputation [30]. Interestingly, 56.1% of the subject would be willing to pay for a cure while 71% of participants were still willing to pay for a cure even if the treatment would be costly showing that cost was not a factor from preventing them seeking medical help.…”

Section: Level Of Awareness Of Participants Towards Nail Infectionmentioning

confidence: 99%

A survey of nail infection and awareness among non-diabetic patients in Mauritius

Oomar¹,

Jeewon²

2013

Our Dermatol Online

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Introduction: Nail infection like onychomycosis is mainly caused by dermatophytes and account for almost half of all nail disorders. Prevalence of nail infection has been attributed to several factors such as age, gender, socioeconomic status and predisposition to diabetes amongst others. This study aims at determining the prevalence and level of awareness of non-diabetics towards nail infections in Mauritius. Material and Methods: A survey was carried out among 471 participants of the non-diabetic population of Mauritius. Data on socio demographic factors, awareness, level of hygiene, family history and quality of life were obtained via questionnaire based studies. Data was analysed using the SPSS software. Results: Results show almost the same ratio of female to male was affected with nail infection but varies gender wise. Participants within the age group 20-60 with less than US 500 monthly income had a higher incidence of nail infection. No significant relation was obtained between nail infection and education level. A significant relationship was obtained between nail infection and occupation as well as quality of life. More than half of participants did not know about the routes of nail infections or the precautions needed to avoid spreading. However, good level of hygiene was observed among the participants. Conclusion: Factors like age, gender and socio economic status had a significant relationship on nail infection. Nail infection affects the Quality of Life (QoL) and manual workers or even professionals are prone to nail infections.

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Diabetic Foot Disorders: A Clinical Practice Guideline (2006 Revision)

Cited by 783 publications

References 435 publications

Skin and soft tissue infections in hospitalised patients with diabetes: culture isolates and risk factors associated with mortality, length of stay and cost

Skin and soft tissue infections in hospitalised patients with diabetes: culture isolates and risk factors associated with mortality, length of stay and cost

Early debridement and skin grafting in diabetic ulcer to reduce morbidity.

A survey of nail infection and awareness among non-diabetic patients in Mauritius

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