Diabetic gastroenteropathy: modern methods of diagnosis and treatment

Kuznetsov, K.O.; Mikheeva, A Ju; Ishmukhametova, A A; Tolstykh, T A; Gallyametdinova, A R; Botirova, Z U; Zabirova, A A; Sharipova, A Sh; Shaikhlislamova, A B; Abdrakhmanova, D R

doi:10.14341/probl13082

Cited by 5 publications

(3 citation statements)

References 56 publications

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“…This results in dysfunction and chronic damage to blood vessels, the brain, nerves, as well as other tissues and organs of the body. As a result, most diabetic patients have gastrointestinal dysfunction in the early or late stages of the disease 2 .…”

Section: Prefacementioning

confidence: 99%

Prevalence of gastroparesis in diabetic patients: a systematic review and meta-analysis

Li,

Wang,

Long

et al. 2023

Sci Rep

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Although there was no significant heterogeneity in the meta-publication, sensitivity analyses revealed significant heterogeneity. Overall, the prevalence was higher in women (N = 6, R = 4.6%, 95% CI 3.1%, 6.0%, and I2 = 99.8%) than in men (N = 6, R = 3.4%, 95% CI 2.0%, 4.7%, and I2 = 99.6the %); prevalence of type 2 diabetes (N = 9, R = 12.5%, 95% CI 7.7%, 17.3%, and I2 = 95.4%) was higher than type 1 diabetes (N = 7, R = 8.3%, 95% CI 6.4%, 10.2%, and I2 = 93.6%); the prevalence of DGP was slightly lower in DM patients aged over 60 years (N = 6, R = 5.5%, 95% CI 3.3%, 7.7%, and I2 = 99.9%) compared to patients under 60 years of age (N = 12, R = 15.8%, 95% CI 11 15.8%, 95% CI 11.4%, 20.2%, and I2 = 88.3%). In conclusion, our findings indicate that the combined estimated prevalence of gastroparesis in diabetic patients is 9.3%. However, the sensitivity of the results is high, the robustness is low, and there are significant bias factors. The subgroup analysis revealed that the prevalence of DM-DGP is associated with factors such as gender, diabetes staging, age, and study method.

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Section: Prefacementioning

confidence: 99%

Prevalence of gastroparesis in diabetic patients: a systematic review and meta-analysis

Li,

Wang,

Long

et al. 2023

Sci Rep

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show abstract

“…Therefore, optimal control of blood glucose in patients with DGP may reduce the risk of future exacerbation of gastroparesis ( 1 ). The goal of blood glucose control should be controlled below 180 mg/dL to avoid inhibiting gastric myoelectric control and movement ( 38 , 42 ).…”

Section: Discussionmentioning

confidence: 99%

The role of diet in diabetes gastroparesis treatment: a systematic review and meta-analysis

Lin,

Wang,

et al. 2024

Front. Endocrinol.

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BackgroundDiabetic gastroparesis is a common complication in patient with diabetes. Dietary intervention has been widely used in the treatment of diabetic gastroparesis. The aim of this study is to evaluate the role of diet in the treatment of diabetic gastroparesis.MethodsThis systematic review was conducted a comprehensive search of randomized controlled trials using dietary interventions for the treatment of diabetic gastroparesis up to 9 November 2023. The primary outcomes were gastric emptying time and clinical effect, while fasting blood glucose, 2-hour postprandial blood glucose and glycosylated hemoglobin were secondary outcomes. Data analysis was performed using RevMan 5.4 software, and publication bias test was performed using Stata 15.1 software.ResultsA total of 15 randomized controlled trials involving 1106 participants were included in this review. The results showed that patients with diabetic gastroparesis benefit from dietary interventions (whether personalized dietary care alone or personalized dietary care+routine dietary care). Compared with routine dietary care, personalized dietary care and personalized dietary care+routine dietary care can shorten the gastric emptying time, improve clinical efficacy, and reduce the level of fasting blood glucose, 2-hour postprandial blood glucose and glycosylated hemoglobin.ConclusionsLimited evidence suggests that dietary intervention can promote gastric emptying and stabilize blood glucose control in patients with diabetic gastroparesis. Dietary intervention has unique potential in the treatment of diabetic gastroparesis, and more high-quality randomized controlled trials are needed to further validate our research results.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023481621.

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“…При СД 2 развитие ГЭРБ обусловлено снижением давления в кардиальном сфинктере, так как гипергликемия увеличивает время переходных расслаблений пищеводного сфинктера. Резкое повышение или снижение (вдвое) уровня глюкозы крови может вызывать соответственно задержку либо ускорение опорожнения желудка, тем самым увеличивая давление в желудке [50].…”

Section: инсулинорезистентностьunclassified

The relationship between gastroesophageal pathogenic reflux and metabolic syndrome

Bulgakova,

Shrayner,

Khavkin

et al. 2024

ECG

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Currently, special attention is drawn to the phenomenon of comorbidity of chronic non-infectious diseases. The emergence of comorbidity is facilitated by the high incidence of coexisting diseases. One such combination is GERD and metabolic syndrome (MS). GERD and MS are multifactorial diseases, the pathogenesis of which is intertwined and mutually aggravates each other. Every year throughout the world and the Russian Federation, there is a clear trend towards an increase in the incidence of pathology of the upper gastrointestinal tract, namely gastroesophageal reflux disease (GERD). The prevalence of obesity in Russia over 40 years of observation has increased 4 times among men and 1.5 times among women. Despite the high incidence, to date there is no diagnosis of “metabolic syndrome” (MS) in ICD-10. MS is coded based on its constituent pathologies (obesity, dyslipidemia, insulin resistance, arterial hypertension). Treatment of this comorbid pathology requires a multidisciplinary approach, thereby placing a high burden on the healthcare system. This article displays the features of the pathogenesis and clinical picture of GERD, as well as the combination of this pathology with the components of MS.

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Diabetic gastroenteropathy: modern methods of diagnosis and treatment

Cited by 5 publications

References 56 publications

Prevalence of gastroparesis in diabetic patients: a systematic review and meta-analysis

Prevalence of gastroparesis in diabetic patients: a systematic review and meta-analysis

The role of diet in diabetes gastroparesis treatment: a systematic review and meta-analysis

The relationship between gastroesophageal pathogenic reflux and metabolic syndrome

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