Diabetic osteopathy

Abstract

Literature data are contradictory concerning the occurrence of bone fractures in diabetic patients. A survey of bone fracture occurrence in diabetic patients was performed in "Veljko Vlahović Medical Center" in Vrbas and it included a group of 100 patients with diabetic disease. The results show that 12 patients had some fractures: mostly females in postmenopause, aged and with secondary insulin-dependent diabetes and most frequently arm fractures. Considering contradictory literature data, further longitudinal studies are necessary.

Insulin-like growth factor-1 in correlation with bone mineral density among Egyptian adolescents with type 1 diabetes mellitus

“…Our findings suggest that vitamin D deficiency is not the cause of diabetic osteopathy in our patients group, although alterations of calcium and Vitamin D3 balance have been implicated as contributing factors of diabetic osteopenia by some but not all authors [47][48][49][50] and even shortly after diagnosis with T1D children presented with decreased lumbar spine BMD and decreased bone formation markers concentration of the carboxy-terminal propeptide of type I collagen [51]. In most studies biochemical parameters of calcium and bone metabolism showed no clear relationship to the bone mineral density measurements [52,53]. From few bone histology studies in humans and experimental studies there is evidence that a decreased bone formation is one major mechanism leading to reduced bone mass in diabetics.…”