1998
DOI: 10.1093/qjmed/91.11.733
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Diabetic peripheral neuropathy and quality of life

Abstract: The quality of life (QOL) of 79 people with type 1 and type 2 diabetes and 37 non-diabetic controls was assessed using the Nottingham Health Profile (NHP). The NHP consists of six domains assessing energy, sleep, pain, physical mobility, emotional reactions and social isolation. Symptomatic diabetic neuropathy was present in 41 of the patients. The neuropathy patients had significantly higher scores (impaired QOL) in 5/6 NHP domains than either the other diabetic patients (p < 0.01) or the non-diabetic (p < 0.… Show more

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Cited by 227 publications
(193 citation statements)
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“…Benbow et al (1998) [30] noted that painful diabetic neuropathy has a considerable impact on QOL. Pain was associated with a reduction in sleep, walking and ability to perform domestic duties.…”
Section: Discussionmentioning
confidence: 99%
“…Benbow et al (1998) [30] noted that painful diabetic neuropathy has a considerable impact on QOL. Pain was associated with a reduction in sleep, walking and ability to perform domestic duties.…”
Section: Discussionmentioning
confidence: 99%
“…Neuropathy contributes the greatest morbidity and mortality and severely impairs the quality of life (3,4) because of paresthesia, pain, and neuropathic injury, the leading cause of nontraumatic amputation in the U.S. Hyperglycemia is critical for the development and progression of diabetic neuropathy (1,2), with the two main pathogenic hypotheses focusing on a metabolic vs. vascular etiology. Despite many studies of human and experimental diabetic neuropathy, the current therapeutic arsenal is very poor.…”
mentioning
confidence: 99%
“…Although diabetic peripheral neuropathy results in severe morbidity, few studies have assessed the quality of life of patients with diabetic peripheral neuropathy (5). The focus of those few reports has been on extreme manifestations of neuropathy such as severe unremitting pain (6,7), chronic foot ulceration (8,9), and/or amputations (10 -13), and virtually no reports have addressed the full spectrum of diabetic peripheral neuropathy severity. Second, when functional status has been measured, the instruments used were generic rather than specific, e.g., the Nottingham Health Profile (14), the Sickness Impact Profile (15), the Short Form (SF)-36 (16), and the EUROQoL, EQ-5D (17).…”
mentioning
confidence: 99%