Diabetics on hemodialysis in El-Minia Governorate, Upper Egypt: five-year study

El-Minshawy, Osama; Kamel, Emad G.

doi:10.1007/s11255-010-9713-z

Cited by 7 publications

(4 citation statements)

References 20 publications

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“…The incidence of end-stage renal failure secondary to diabetes mellitus is increasing globally [63][64][65]. It is probable that severe derangements in serum glucose concentration in patients on chronic dialysis will also increasingly require the attention of nephrologists.…”

Section: Discussionmentioning

confidence: 99%

Abnormalities of serum potassium concentration in dialysis-associated hyperglycemia and their correction with insulin: review of published reports

et al. 2010

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The main difference between dialysis-associated hyperglycemia (DH) and diabetic ketoacidosis (DKA) or nonketotic hyperglycemia (NKH) occurring in patients with preserved renal function is the absence of osmotic diuresis in DH, which eliminates the need for large fluid and solute (including potassium) replacement. We analyzed published reports of serum potassium (K(+)) abnormalities and their treatment in DH. Hyperkalemia was often present at presentation of DH with higher frequency and severity than in hyperglycemic syndromes in patients with preserved renal function. The frequency and severity of hyperkalemia were higher in DH episodes with DKA than those with NKH in both hemodialysis and peritoneal dialysis. For DKA, the frequency and severity of hyperkalemia were similar in hemodialysis and peritoneal dialysis. For NKH, hyperkalemia was more severe and frequent in hemodialysis than in peritoneal dialysis. Insulin infusion corrected the hyperkalemia of DH in most cases. Additional measures for the management of hyperkalemia or modest potassium infusions for hypokalemia were needed in a few DH episodes. The predictors of the decrease in serum K(+) during treatment of DH with insulin included the starting serum K(+) level, the decreases in serum values of glucose concentration and tonicity, and the increase in serum total carbon dioxide level. DH represents a risk factor for hyperkalemia. Insulin infusion is the only treatment for hyperkalemia usually required.

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Section: Discussionmentioning

confidence: 99%

Abnormalities of serum potassium concentration in dialysis-associated hyperglycemia and their correction with insulin: review of published reports

et al. 2010

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“…It is comparable with its prevalence in Saudi Arabia, where it affects more than 25% of the adult population. [22] As well, hypertension represents a major cause of ESRD in other regional countries such as Egypt [23] , Turkey [24] and Iran. [25] In the US, hypertension represents 28% of the causes of ESRD cases.…”

Section: Discussionmentioning

confidence: 99%

Family history in patients with end-stage renal disease on hemodialysis in Tripoli, Libya

Elamouri

2021

Ibnosina Journal of Medicine and Biomedical Sciences

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Background: End-Stage Renal Disease (ESRD) is a global health problem due to increasing its burden worldwide. High-risk groups include family members of patients with ESRD. Objectives: To determine the prevalence of ESRD among dialysis patients' families. At Al-Shat kidney dialysis Center, Tripoli, Libya. So can conclude that the ESRD patient is an index case for a high- risk population. Methods: All patients' data were collected through direct interview with the patients for 15- 20 minutes and by reviewing patients' charts. Patients who decline consent to participate and those with mental or speech disability were excluded, and patients on peritoneal dialysis. The study carried at Al-Shat kidney dialysis centre, Tripoli, Libya. In January 2019. Results: 261 patients were interviewed, mean age 51.8 years (±15), nearly half (48.7%) of them, between 45 to 65 years and 31.8% younger than 45 years. 56.3% were men, and 43.7% were women. The leading causes of ESRD in these patients were DM, HTN, congenital abnormalities (APCKD/VUR) and GN (35.2%, 22.2%, 10%, 8%). Positive family history of ESRD was reportedby 26.8% of these patients. From them, 47% (33/70) were between 45 to 65 years ofage. 58.6% were male (41/70). 34.3% have diabetic, 20% have HTN, 13%have congenital abnormalities, and 7% GN. Conclusions: Positive familyhistory of ESRD was high in dialysis patients. These patients can be used as anindex case to identify high- risk population.

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“…CKD arising in the absence of diabetes, hypertension and other known risk factors is referred to as chronic kidney disease of uncertain etiology (CKDu) (2). CKDu has been detected in Central America, Egypt, India, and Sri Lanka (3)(4)(5)(6). While several hypotheses are being explored to uncover the causative agents/factors responsible for CKDu, a hypothesis that has been overlooked in Sri Lanka is an infectious etiology, such as hantavirus infection and leptospirosis (7).…”

Section: Introductionmentioning

confidence: 99%

Insufficient serological evidence of the association between chronic kidney disease and leptospirosis in Badulla and Kandy districts, Sri Lanka

Fonseka

Senarathne

Muthusinghe

et al. 2023

Preprint

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Chronic kidney disease (CKD) and chronic kidney disease of uncertain etiology (CKDu) are chronic renal diseases that pose a significant health burden in Sri Lanka. Leptospirosis is a bacterial zoonosis that primarily damages kidney tissues via colonization of Leptospira spp. in the renal tubules and is a suspected etiological agent of CKDu. Since Sri Lanka is a leptospirosis endemic country where outbreaks of the disease have been reported, this study aimed to find the association between leptospirosis and chronic renal disease in two geographically distinct regions of Sri Lanka, Kandy (CKDu non-endemic) and Badulla (CKDu endemic) districts. Forty-nine chronic renal disease patients and 135 controls from Kandy and 89 chronic renal disease patients and 149 controls from Badulla were examined serologically by microscopic agglutination test with a panel of 11 Leptospira serogroups. A seroprevalence of 35.3% and 32.5% for leptospirosis was observed in the Girandurukotte CKDu group and Girandurukotte control group respectively, while a seroprevalence of 36.7% and 31.9% were observed in the Kandy CKDu group and Kandy control group respectively. No statistically significant differences in leptospirosis seropositivity were observed between the chronic renal disease and control groups in both districts. However, further longitudinal studies assessing renal colonization among chronic renal patients and healthy individuals are required to conclusively state whether leptospirosis plays an important role in chronic renal disease development and/or progression in Sri Lanka.

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Diabetics on hemodialysis in El-Minia Governorate, Upper Egypt: five-year study

Cited by 7 publications

References 20 publications

Abnormalities of serum potassium concentration in dialysis-associated hyperglycemia and their correction with insulin: review of published reports

Abnormalities of serum potassium concentration in dialysis-associated hyperglycemia and their correction with insulin: review of published reports

Family history in patients with end-stage renal disease on hemodialysis in Tripoli, Libya

Insufficient serological evidence of the association between chronic kidney disease and leptospirosis in Badulla and Kandy districts, Sri Lanka

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