Objective
Individuals experience chronic pain differently, not only based on different clinical diagnosis, but also on differing degrees of influence by biopsychosocial pain modulators. We aimed to cluster chronic pain patients into distinct subgroups based on psychosocial characteristics and pain intensity, and subsequently examined group differences in pain-related interference approximately one year later.
Methods
In this observational, longitudinal study, patients with chronic pain (N = 94) completed validated assessments of psychosocial characteristics and pain intensity at the beginning of COVID-related social distancing (April-June, 2020). One year later (May-June, 2021), patients completed a follow-up survey with assessments of pain interference, loneliness, social support, mindfulness, and optimism.
Results
A cluster analysis, using psychosocial factors and pain intensity, empirically produced three patient groups: 1) PsychoSocial Predominant (PSP), characterized by high psychosocial distress and average pain intensity; 2) Pain Intensity Predominant (PIP), characterized by average psychosocial distress and high pain intensity; and 3) Less Elevated Symptoms (LES), characterized by low psychosocial distress and low pain intensity. At the 1-year follow-up, patients in the PSP and PIP clusters suffered greater pain interference compared to the LES cluster, while the PSP cluster also reported greater loneliness, and lower mindfulness and optimism.
Conclusions
An empiric psychosocial-based clustering of patients identified three distinct groups, which differed in pain interference. Patients with high psychosocial modulation of pain at the onset of social distancing (PSP cluster) suffered not only greater pain interference, but also greater loneliness and lower levels of mindfulness and optimism, suggesting some potential behavioral targets for this group in the future.