Diagnosing Chronic Pancreatitis

Anaizi, Ahmad; Hart, Phil A.; Conwell, Darwin L.

doi:10.1007/s10620-017-4493-2

Cited by 46 publications

(29 citation statements)

References 35 publications

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“…However, another study of the same cohort reported a very poor correlation between EUS features and the degree of fibrosis determined by histopathology, suggesting that EUS is less accurate than previously believed [37]. Therefore, EUS alone is not recommended to establish a clinical diagnosis of chronic pancreatitis; the diagnosis should be made in concert with the clinical presentation, laboratory analysis, and cross-sectional imaging [38].…”

Section: Update In the Diagnosis Of Chronic Pancreatitismentioning

confidence: 99%

Recent advances in the diagnosis and management of chronic pancreatitis

Kwon

Cho

Choi

et al. 2019

Korean J Intern Med

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Chronic pancreatitis is a chronic condition characterized by pancreatic inflammation that causes fibrosis and the destruction of exocrine and endocrine tissues. Chronic pancreatitis is a progressive disease, and no physiological treatment is available to reverse its course. However, with advances in medical technology, the existing diagnostic and treatment methods for chronic pancreatitis are evolving. Managing patients with chronic pancreatitis is challenging and necessitates a multidisciplinary approach. In this review, we discuss the recent advances in the diagnosis and management of chronic pancreatitis and introduce future alternative modalities.

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Section: Update In the Diagnosis Of Chronic Pancreatitismentioning

confidence: 99%

Recent advances in the diagnosis and management of chronic pancreatitis

Kwon

Cho

Choi

et al. 2019

Korean J Intern Med

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“…The pain pattern among those with abnormal results differed from the pain of typical irritable bowel syndrome as it was more often described as radiating through to the back and waking them from sleep and less likely to be post‐prandial . Distinguishing between pancreatic pain and pain related to irritable bowel syndrome has become easier since the introduction of more accurate tests such as computed tomography or endoscopic ultrasound . Currently, assessment for pancreatic disease is often included in the evaluation of those with suspected functional dyspepsia especially if the pain pattern or other features are atypical.…”

Section: Pancreatic Function In Irritable Bowel Syndrome‐like Conditionsmentioning

confidence: 99%

“…10 Distinguishing between pancreatic pain and pain related to irritable bowel syndrome has become easier since the introduction of more accurate tests such as computed tomography or endoscopic ultrasound. [11][12][13] Currently, assessment for pancreatic disease is often included in the evaluation of those with suspected functional dyspepsia especially if the pain pattern or other features are atypical.…”

Section: Pancreatic Function In Irritable Bowel Syndrome-like Condimentioning

confidence: 99%

Enzyme therapy for functional bowel disease‐like post‐prandial distress

Graham

Ketwaroo

Money

et al. 2018

J of Digest Diseases

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Post-prandial gastrointestinal symptoms such as diarrhea, abdominal distension, flatulence, bloating and a feeling of fullness are common complaints of often unknown etiology and pathogenesis. There is a long history of trials reporting the successful use of products containing a variety of combinations of digestive enzymes including a number of randomized placebo-controlled trials. We provide a narrative review of studies describing the use of multi-digestive enzymes for symptoms consistent with irritable bowel syndrome. We describe clinical trials reported over the past 60 years including double-blinded randomized, placebo-controlled studies and recent trials that focused on post-prandial diarrhea consistent with diarrhea-predominant irritable bowel syndrome. Disaccharidase deficiencies or deficiencies of other carbohydrate digesting enzymes were excluded. Worldwide studies have generally reported success with multi-enzyme preparations although none used a factorial design to identify subgroups or attempted to link specific symptom responses to specific components of therapy. Although there is a long history of the successful use of multi-enzyme preparations for post-prandial symptoms consistent with irritable bowel syndrome, long-term studies using validated scoring systems and factorial designs are needed to confirm the results for specific symptoms and the components of the combination drugs received.

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“…Perfusion MRI, DWI, and FDG/PET can be helpful in such cases. Nevertheless, the common clinical presentation with chronic abdominal pain in chronic pancreatitis does not correlate very well with imaging findings [26][27][28][29][30]. …”

Section: Acute and Chronic Pancreatitismentioning

confidence: 99%