1997
DOI: 10.3322/canjclin.47.2.70
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Diagnosing colorectal carcinoma: clinical and molecular approaches

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Cited by 34 publications
(13 citation statements)
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References 142 publications
(282 reference statements)
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“…Adenocarcinoma of the colon and rectum is the third most common malignancy in North America, with a rising incidence over the past decade [1]. Liver metastases occur either synchronous or metachronous to presentation of the primary tumor in up to one-third of patients [2].…”
Section: Introductionmentioning
confidence: 99%
“…Adenocarcinoma of the colon and rectum is the third most common malignancy in North America, with a rising incidence over the past decade [1]. Liver metastases occur either synchronous or metachronous to presentation of the primary tumor in up to one-third of patients [2].…”
Section: Introductionmentioning
confidence: 99%
“…Em nossa experiência, nem a idade nem o sexo mostraram ser fatores prog- (20) encontraram pior sobrevida no grupo de idosos acima de 75 anos portadores de câncer colorretal, tendo relacionado o achado ao diagnóstico tardio. Da mesma forma, também atribuindo ao retardo no diagnóstico, com 66% dos pacientes em estágios III e IV da doença -porém associado com tumores mais agressivos, -o grupo etário mais jovem (abaixo de 40 anos) também tem sido relacionado a piores prognósticos (2,12,21,22) , com altas taxas de mortalidade (25% num seguimento mé-dio de 26 meses) (23) . No entanto, parece que esse efeito é minimizado quando a análise de sobrevida é ajustada de acordo com o estágio do tumor (12) .…”
Section: Discussionunclassified
“…Approximately, 55% of colorectal cancers diagnosed on screening are found to present with Stage I or II disease. 2,3 Patients with Stage I or Stage II colon cancer have a greater than 60% 5-year survival, and for patients with Stage I or Stage II rectal cancer, there is a greater than 50% 5-year survival. 4,5 Because of this, colorectal screening exams in asymptomatic patients have become the recommended standard of care for average risk patients at the age of 50 and at the age of 40 or younger for those in the moderate and high risk groups.…”
Section: Introductionmentioning
confidence: 99%