Diagnosing detrusor sphincter dyssynergia in the neurological patient

Sacral neuromodulation: an effective treatment for lower urinary tract symptoms in multiple sclerosis

“…In view of the high intravesical pressure, chronic urinary retention and recurrent urinary tract infections (UTIs) are experienced by these patients, and upper urinary tract complications such as renal failure, pyelonephritis, hydronephrosis, and bladder and kidney stones have been described in 5 -10 % of patients with MS [3,7]. Further results have shown that if the DSD and chronic urinary retention are not treated, up to 50 % of patients with MS might develop the above complications [8,9]. Therefore, a detailed assessment of bowel, bladder and sexual function in MS patients is mandatory in order to prevent complications and subsequent morbidities as well as to improve their QoL [1,3].…”

Diagnostic accuracy of single channel cystometry for neurogenic bladder diagnosis following spinal cord injury: a pilot study

“…2,12,15 Serious urological complications such as reduced bladder compliance, elevated upper tract pressures, hydronephrosis, vesicoureteral reflux and even renal failure have been associated with improperly managed DSD. 2,12,15 Thus, the role of UDS is critical as it provides not only a confirmatory diagnosis of DSD, additionally it is also able to monitor the outcome of intervention. 15 Therefore, the authors recommended that it is mandatory for all patients with clinical or SCC suspicion of having DSD, to have early UDS for confirmation of diagnosis so that proper bladder management strategies are instituted in a timely manner.…”

“…2,12,15 Thus, the role of UDS is critical as it provides not only a confirmatory diagnosis of DSD, additionally it is also able to monitor the outcome of intervention. 15 Therefore, the authors recommended that it is mandatory for all patients with clinical or SCC suspicion of having DSD, to have early UDS for confirmation of diagnosis so that proper bladder management strategies are instituted in a timely manner.…”

Management of Lower Urinary Tract Dysfunction in Patients with Neurological Disorders

“…Occasionally, flow may be prevented altogether [49]. DSD more commonly occurs in the neurological abnormalities between the pontine micturition center and sacral spinal cord, including SCI, multiple sclerosis, and spina bifida [54]. If DSD is left untreated, over half of patients develop serious urological complications such as high bladder pressure, reduced bladder compliance, VUR, hydronephrosis, and renal failure [54].…”