Diagnosis and analysis of primary central nervous system lymphoma based on MRI segmentation algorithm

Abstract

Objective: This paper summarizes the MRI imaging findings of primary central nervous system lymphoma (PCNSL) in the posterior cranial fossa to improve the accuracy of PCNSL diagnosis in the posterior cranial fossa.
 Methods: This study retrospectively analyzed the MRI imaging manifestations of 15 PCNSL posterior cranial fossa cases confirmed by puncture or surgical pathology from June 2017 to May 2018, including their occurrence sites, the number of lesions, MRI plain and enhanced manifestations, and diffusion-weighted imaging (DWI) and magnetic resonance spectroscopy. Imaging (MRS) performance.
 Results: A total of 15 cases were enrolled, including 10 cases of single lesion and five cases of multiple lesions. The total number of lesions was 25, which were in the cerebellar hemisphere and cerebellar vermis, midbrain, fourth ventricle, and pontine cerebellum. The lesions were round, irregular, nodular, patchy, with low or medium signals on T1WI, equal or slightly higher signals on T2WI, and enhanced with 25 meningiomas-like gray matter signals. All of them were significantly strengthened. “Acupoint sign” and “umbilical depression sign” were seen in eight lesions. There were 17 massive and nodular enhancements, four striped enhancements, three patchy enhancements, and one circular enhancement. five cases of DWI showed homogeneous high signal, two cases showed uneven high signal, and 3 cases showed medium signal. The ADC value of tumor parenchyma in 10 patients was (0.62±0.095)×10-3mm2/s. MRS examination showed obvious Lip peak in two cases.
 Conclusion: PCNSL in posterior cranial fossa has certain characteristics. DWI, ADC value and MRS are helpful to improve the correct diagnosis rate of PCNSL.
 doi: https://doi.org/10.12669/pjms.37.6-WIT.4843
 How to cite this:Lu G, Li Y, Liang X, Zhao Z. Diagnosis and analysis of primary central nervous system lymphoma based on MRI segmentation algorithm. Pak J Med Sci. 2021;37(6):1585-1589. doi: https://doi.org/10.12669/pjms.37.6-WIT.4843
 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Primary central nervous system diffuse large B-cell lymphoma in fourth ventricle: Case report and literature review

“…In some cases, the tumor may disappear after using glucocorticoid. [ 9 ] The identification points of various common tumors and lymphomas of the fourth ventricle have been listed in the following table (Table 1 ).…”

Posterior fossa epidural hematoma: A 6-year management experience

“…While among children, the increased vulnerability to injury and the higher incidence is mainly due to the anatomical proximity in the dura and venous sinus. 9,10 Cranial CT scan contributes to the early diagnosis of PFEDH; it is an effective imaging technique and has a short acquisition time. It is evident from the existing literature that the CT efficiently determines the size of the hematoma and associated occipital bone fracture; it also tells us about compression of the posterior fossa structures and hydrocephalous, which may need surgical intervention.…”

“…While among children, the increased vulnerability to injury and the higher incidence is mainly due to the anatomical proximity in the dura and venous sinus. 9 , 10…”

“…8 A few studies also define delayed extradural hematoma development in relation to bleeding of venous origin. 9 Unilateral mydriasis is among the most frequent misleading signs observed among PDEFH patients, which could be explained by the deformation of tentorial hiatus and oculomotor nerve compression causing cerebellum upward herniation. 6 Computed tomography (CT) of the brain has been recognized as the vital diagnostic modality for PFEDH.…”

Diagnostic value of Video Electroencephalography combined with Magnetic Resonance Imaging-diffusion tensor imaging in epilepsy

“…The technique results in clear images without radiation exposure. 11 , 12 Studies have investigated VEEG combined with functional MRI (fMRI) 13 , 14 , or DTI combined with functional MRI 15 , but few on VEEG plus MRI-DTI. Therefore, we aimed to retrospectively analyze the clinical data of 55 patients with epilepsy in our hospital to assess the diagnostic value of VEEG combined with MRI-DTI for epilepsy.…”