Diagnosis and Impact of Hilar Lymph Node Micrometastases on the Outcome of Resected Colorectal Liver Metastasis

Abstract

Microscopic LN metastases may have impact in the outcome of patients submitted to curative hepatectomy. A better definition of micrometastases to LN is warranted, as though the potential benefit of hilar lymphadenectomy and chemotherapy selection by hilar lymph node status.

Intrahepatic Lymphatic Invasion but not Vascular Invasion is a Major Prognostic Factor after Resection of Colorectal Cancer Liver Metastases

“…The frequency and prognostic implication of hepatic pedicle lymph node invasion as the indication, extent, and therapeutic role of hilar lymphadenectomy are presently the objects of ongoing interest [21–24]. Unfortunately, the retrospective character of our study did not allow us to evaluate the relationship between the presence of hilar lymph node invasion and LVI.…”

“…The frequency and the prognostic implication of hepatic pedicle lymph nodes invasion as though as the indication, extent, and therapeutic role of hilar lymphadenectomy are presently the objects of ongoing interest [21][22][23][24].…”

Metástases hepáticas de câncer colorretal: estudo do impacto prognóstico das vias de disseminação tumoral e da presença de mucina em pacientes submetidos à ressecção hepática com intenção curativa

“…Nenhum dos escores de risco atualmente disponiveis pode, de maneira confiável, interferir na proposta cirúrgica em um paciente com MH ressecáveis (Zakaria S, et al, 2007;Gregoire E, et al, 2010). (Viana E, et al, 2011;Lupinacci RM, et al, 2013;Herman P, et al, 2013;Pinheiro RS, et al, 2014;Lupinacci RM, et al, 2014a;Lupinacci RM, et al, 2014b). (Jass JR, et al, 1987).…”