Diagnosis and management of henoch-schönlein purpura in pregnancy: a review of the literature

Tayabali, Sarrah; Andersen, Kathryn; Yoong, Wai

doi:10.1007/s00404-012-2468-2

Cited by 20 publications

(10 citation statements)

References 19 publications

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“…Nine were new cases diagnosed either during pregnancy (n=8) or postpartum (n=1), and the remainders were relapses. In 6 relapse cases, pregnancy occurred during disease exacerbation and 2 of these experienced spontaneous remission during pregnancy [6,[10][11][12]17]. Complications were frequent with only 8/20 having uncomplicated term deliveries.…”

Section: Discussionmentioning

confidence: 99%

“…Prednisone is often favored over methylprednisolone during pregnancy, as transplacental passage occurs in small amounts, reducing the risk of fetal adverse effects [2,23]. Among the 20 cases of HSP during pregnancy, half were treated with steroids, leading to rapid resolution of purpura, abdominal symptoms or arthralgia [6]. Plasmapheresis was effectively used in one relapse case [24].…”

Section: Discussionmentioning

confidence: 99%

“…Plasmapheresis was effectively used in one relapse case [24]. Hemodialysis was successfully used in one case where HSP was diagnosed at 23 weeks gestation and hypertension, anasarca and renal failure appeared at 32 weeks [6].…”

Section: Discussionmentioning

confidence: 99%

“…It is primarily a childhood disease [1][2][3][4][5][6], characterized by purpuric lesions on the lower limbs, episodic abdominal pain, arthritis, fever, malaise and glomerulonephritis with proteinuria and hematuria. Extra-renal manifestations include headaches, seizures and encephalopathy.…”

Section: Introductionmentioning

confidence: 99%

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Henoch Schönlein Purpura in Pregnancy: a Case with Uncomplicated Maternal and Neonatal Outcome

Tejada¹,

McCarey²,

Boehlen³

et al. 2015

Int. J. Gynecol. Obstet. & Neona. Care

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Abstract:Introduction: Henoch-Schönlein Purpura (HSP) is a systemic IgA-mediated small-vessel vasculitis. It is primarily a childhood disease, rarely described in pregnancy. Pregnant women with HSP are at risk for hypertensive and hemorrhagic complications. Due to the rarity of the condition during pregnancy, there is no consensus about the preferred course of treatment but concerns regarding optimal management are ongoing.Case presentation: We report the case of an 18 year-old primigravida, with a 3-year history of HSP, who had an uneventful pregnancy and term delivery with epidural anesthesia. Conclusion:Due to the systemic nature of HSP, multidisciplinary management of pregnant HSP patients should be warranted to prevent complications.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Henoch Schönlein Purpura in Pregnancy: a Case with Uncomplicated Maternal and Neonatal Outcome

Tejada¹,

McCarey²,

Boehlen³

et al. 2015

Int. J. Gynecol. Obstet. & Neona. Care

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“…HSP is rarely described in pregnancy ( 12 - 15 ). The occurrence of HSP in pregnancy can affect the mother and the foetus.…”

Section: Introductionmentioning

confidence: 99%

Henoch-Schönlein purpura in the third trimester of pregnancy

Djaković

Butorac²,

Vučičević³

et al. 2017

Biochemia Medica

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Henoch-Schönlein purpura (HSP) is an IgA-mediated small vessels’ vasculitis that affects the skin, intestines and kidneys. Pregnancy has been reported as an exacerbating factor. We present the case of a 24-year-old primigravida with HSP that occurred in the third trimester and lasted up to the end of the successful delivery. She had pruritic maculopapular exanthema on her legs. Biopsy of a cutaneous lesion was performed for histopathologic features and direct immunofluorescence (DIF) for the presence of perivascular IgA deposition. Histopathology of the cutaneous lesion confirmed leukocytoclastic vasculitis. A DIF examination of the skin lesion confirmed deposits of fibrinogen in the small blood vessel walls. Six weeks following delivery, the skin lesions almost completely disappeared. Control laboratory findings were normal. This case of HSP might have been primarily associated with a preceding respiratory infection but this should first be carefully investigated due to a possible severe immunological disease in the patient’s background requiring special attention since nephrotic symptoms may occur.

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IgA Vasculitis Nephritis (Henoch-Schönlein Purpura Nephritis)

Shin

2023

Pediatric Kidney Disease

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Diagnosis and management of henoch-schönlein purpura in pregnancy: a review of the literature

Abstract: We review the obstetric cases reported so far and discuss diagnostic matters and current management strategies.

Cited by 20 publications

References 19 publications

Henoch Schönlein Purpura in Pregnancy: a Case with Uncomplicated Maternal and Neonatal Outcome

Henoch Schönlein Purpura in Pregnancy: a Case with Uncomplicated Maternal and Neonatal Outcome

Henoch-Schönlein purpura in the third trimester of pregnancy

IgA Vasculitis Nephritis (Henoch-Schönlein Purpura Nephritis)

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