“…Cyst fluid spillage can occur during surgery resulting in anaphylaxis and/or secondary echinococcosis (2%-25% of cases). 10,[33][34][35] Two benzimidazoles (mebendazole and albendazole) and praziquantel, an isoquinolone derivative, have scolicidal activity and have been used in over 1000 well-documented patients with cystic hydatid disease. Mebendazole is poorly absorbed, and scolicidal drug levels are achieved with a daily dose of 40-50 mg/kg administered orally in divided doses.…”