Diagnosis and management of pre-eclampsia: an update

Turner, Jon

doi:10.2147/ijwh.s8550

Cited by 176 publications

(126 citation statements)

References 56 publications

(86 reference statements)

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“…9 It was widely demonstrated that gestational age at birth had a major impact on perinatal outcome. 10 Perinatal mortality and morbidity were demonstrated to be higher in women with EO-PE.…”

Section: Discussionmentioning

confidence: 99%

Early onset and late onset preeclampsia-maternal and perinatal outcomes in a rural teritiary health center

Gomathy¹,

Akurati²,

Kannan³

2018

Int J Reprod Contracept Obstet Gynecol

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Background: Preeclampsia is main cause of morbidity and mortality both mother and fetus. Preeclampsia occurs in 10-17% of pregnancies. Preeclampsia was divided into early onset preeclampsia is occur at less <34 weeks of gestation age and late onset preeclampsia is occur at >34 weeks of gestation age. Early and late onset preeclampsia have different etiology and should be considered as different disease as there are difference in clinical manifestation, maternal and perinatal outcome, prognosis and complication.Methods: An analytic observational study involving retrospective data done at RL Jalappa Hospital, Sri Devaraj Urs Medical College, Kolar. 217 women with singleton pregnancies with Pre eclampsia who were admitted and delivered in our hospital between June 2016 and May 2017 were recruited for this retrospective study.Results: The results showed that the incidence of EOPE (27.6%) was lower than LOPE (72.4%). Diastolic blood pressure is significantly higher in EOPE compared to LOPE. Complications in perinatal outcomes such as low birth weight (<2500 gram) are more in EOPE (98.3%) compared to LOPE (45.2%) and asphyxia is more on EOPE (11.7%) compared to LOPE (1.3%). Stillbirth in EOPE (15%) is more than LOPE group (3.2%).Conclusions: It is observed that EOPE incidence rate is lower than LOPE. Maternal and perinatal complications are greater in the EOPE group.

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Section: Discussionmentioning

confidence: 99%

Early onset and late onset preeclampsia-maternal and perinatal outcomes in a rural teritiary health center

Gomathy¹,

Akurati²,

Kannan³

2018

Int J Reprod Contracept Obstet Gynecol

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“…At the first prenatal visit, it is possible to identify several factors that have been proven to increase the risk of preeclampsia development (see Tab. III) (24,(46)(47)(48)(49). The detection of pregnant women at high risk for preeclampsia involves tighter monitoring of the pregnancy evolution, and some preventive measures may be indicated.…”

Section: Preeclampsia Risk Factors and Preventionmentioning

confidence: 99%

Acute kidney injury in pregnancy: a clinical challenge

Machado¹,

Figueiredo²,

Borges³

et al. 2011

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The incidence of acute kidney injury in pregnancy declined significantly over the second half of the 20th century; however, it is still associated with major maternal and perinatal morbidity and mortality. A set of systemic and renal physiological adaptive mechanisms occur during a normal gestation that will constrain several changes in laboratory parameters of renal function, electrolytes, fluid and acid-base balances. The diagnosis of acute kidney injury in pregnancy is based on the serum creatinine increase. The usual formulas for estimating glomerular filtration rate are not validated in this population. During the first trimester of gestation, acute kidney injury develops most often due to hyperemesis gravidarum or septic abortion. In the third trimester, the differential diagnosis is more challenging for the obstetrician and the nephrologist and comprises some pathologies that are reviewed in this article: preeclampsia/HELLP syndrome, acute fatty liver of pregnancy and thrombotic microangiopathies.

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“…3 Globally, pre-eclampsia and eclampsia account for 10-15% of maternal death. 4 Most of the over half a million maternal deaths that occur annually are in the developing countries like india. 5 Eclampsia is characterized by the sudden onset of generalised tonic clonic seizures.…”

Section: Introductionmentioning

confidence: 99%

Comparative study of vaginal delivery and caesarean section in antepartum eclampsia at tertiary care hospital

Kumari¹,

Singh²,

Khatun³

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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Background: Eclampsia is characterized by the sudden onset of generalized tonic clonic seizures. Eclampsia is usually preceded by a history of the pre-eclampsia but rarely arises in a woman with minimally increased blood pressure and no proteinuria. Eclampsia most commonly occurs in the third trimester, though rarely eclampsia may occur before 20 wks in molar or multiple pregnancy. The aim of the study was to compare maternal and fetal outcome in antepartum eclampsia when terminated by vaginal delivery and caesarean section.Methods: 50 women with eclampsia attending emergency department OBG department of Katihar Medical College, Katihar were collected from Feb 2015 to Sep 2016. Depending upon the mode of delivery, they were divided into two groups, CD group where caesarean section was performed and VD group where vaginal delivery was performed.Results: Of the 50 cases, caesarean section was done in 40% of the cases, while vaginal delivery was carried was carried in 60%.Maternal complications in CD group was 35% and 80% in VD group (p<0.001).The incidence of live births, still birth and neonatal death was 85%, 15%, 0% in CD group and 60%, 40%, 10% in VD group. The corrected perinatal mortality was 50%.Conclusions: Timely caesarean section reduces maternal and perinatal mortality and improves their outcome in antepartum eclampsia.

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Diagnosis and management of pre-eclampsia: an update

Cited by 176 publications

References 56 publications

Early onset and late onset preeclampsia-maternal and perinatal outcomes in a rural teritiary health center

Early onset and late onset preeclampsia-maternal and perinatal outcomes in a rural teritiary health center

Acute kidney injury in pregnancy: a clinical challenge

Comparative study of vaginal delivery and caesarean section in antepartum eclampsia at tertiary care hospital

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