Diagnosis and Management of Toxoplasmosis

Montoya, José G.; Rosso, Fernando

doi:10.1016/j.clp.2005.04.011

Cited by 90 publications

(77 citation statements)

References 43 publications

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“…The issuing of a chronic or latent phase of infection is characterized by the presence of the persistence form (cysts) of the organism in tissues (skeletal muscles, heart and brain). An infected individual who develops a defective cell-mediated immunity is at risk of reactivated infection (1,2,3). In Cameroon such data are scarce, and information used is usually from developed countries.…”

Section: Introductionmentioning

confidence: 99%

“…It has gradually evolved over the pass decades to be among the most common opportunistic diseases in HIV/AIDS in developing countries (2). The prevalence of seropositivity for antibodies against Toxoplasma gondii has been estimated at 3% in Western Europe and 67% to 90% in tropical countries.…”

Section: Introductionmentioning

confidence: 99%

“…The prevalence of seropositivity for antibodies against Toxoplasma gondii has been estimated at 3% in Western Europe and 67% to 90% in tropical countries. Transmission is mainly by ingestion of tissue cysts in raw and undercooked meat, exposure to oocysts in contaminated vegetable or contact with faeces of a felid (2).The development of a cell-mediated immunity after an acute infection results in the control of the disease, but not the eradication of the infection. The issuing of a chronic or latent phase of infection is characterized by the presence of the persistence form (cysts) of the organism in tissues (skeletal muscles, heart and brain).…”

Section: Introductionmentioning

confidence: 99%

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Toxoplasma antibodies amongst HIV/AIDS patients attending the University Teaching Hospital Yaounde in Cameroon

Assob¹,

Njunda²,

Nsagha³

et al. 2011

Af J Clin Exp Micro

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Toxoplasmosis is caused by an obligatory intracellular protozoon. It causes a wide range of diseases with toxoplasma encephalitis commonly encountered in HIV/AIDS patients. This work was carried out to determine the seroprevalence of toxoplasma antibodies (IgM and IgG) in HIV/AIDS patients attending the Yaoundé University Teaching Hospital (UTH) in Cameroon. Sera were collected from 133 HIV/AIDS patients at the out-patient department and the ELISA technique was employed serologically to determine toxoplasma antibodies. Of the 133 patients 83 (62.4%) were females and 59 (37.6%) were males; ninety three (69.9%) were positive for toxoplasma antibodies. Fourteen (10.8%) of the 93 of seropositive patients presented with both IgG and IgM-antibodies in their sera while fifty six (42.1%) and 8 (6.0%) were only sero-positive for toxoplasma IgG or IgM-antibody respectively This rate of infection was not dependent on the patient's sex or age (X 2 =11.49, P>0.05). The data provides enough evidence to conclude that 64.7% of the positive cases were due to reactivated infection.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Toxoplasma antibodies amongst HIV/AIDS patients attending the University Teaching Hospital Yaounde in Cameroon

Assob¹,

Njunda²,

Nsagha³

et al. 2011

Af J Clin Exp Micro

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“…The diagnosis of toxoplasmosis in pregnant woman is based mainly on serological methods to detect specific antibodies 5 . However, as in most other countries, Brazil does not have a free national program to investigate toxoplasmosis during pregnancy, in spite of the high prevalence of the infection.…”

Section: Introductionmentioning

confidence: 99%

Incidence of congenital toxoplasmosis in the city of Belém, state of Pará, northern Brazil, determined by a neonatal screening program: preliminary results

Bichara

Canto

Tostes

et al. 2012

Rev. Soc. Bras. Med. Trop.

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Revista da Sociedade Brasileira de MedicinaABSTRAcT Introduction: The aim of this study was to determinate the incidence of congenital toxoplasmosis among a group of newborns (NBs) from Belém using neonatal screening. Methods: Among the 6,000 newborns referred for investigation of genetic and metabolic diseases, 1,000 were selected for screening for congenital toxoplasmosis by determining the amount of IgM in the eluates of blood collected on filter paper. Positive tests were confirmed using paired serology of the NB and his mother. Results: Out of the 1,000 NBs assessed, one had a positive screening result that was confirmed by paired serology. conclusions: The incidence of congenital toxoplasmosis in Belém was 10/10,000 live NBs.

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“…Ocular toxoplasmosis is characterized by a necrotizing retinitis with oval or circular lesions (4) . It is often impossible to determine the congenital or acquired nature of this particular uveitic process (1)(2)(13)(14)(15) . Late onset acquired ocular toxoplasmosis may manifest itself up until at least thirteen years after primary infection (16 -17) .…”

mentioning

confidence: 99%