1986
DOI: 10.1016/s0003-4975(10)62725-7
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Diagnosis and Recommended Management of Esophageal Perforation and Rupture

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Cited by 275 publications
(144 citation statements)
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“…The overall mortality rate of oesophageal perforation i~rom all causes is approximately 21%, compared with 6% in uncomplicated cervical oesophageal perforation. 3,4 In this case, a tract extending from the retropharyngeal space to the mediastinum was established by the nasogastafc tube. This likely resulted in mediastinal contamination, and so primary repair of the oesophageal laceration was undertaken.…”
Section: Discussionmentioning
confidence: 87%
“…The overall mortality rate of oesophageal perforation i~rom all causes is approximately 21%, compared with 6% in uncomplicated cervical oesophageal perforation. 3,4 In this case, a tract extending from the retropharyngeal space to the mediastinum was established by the nasogastafc tube. This likely resulted in mediastinal contamination, and so primary repair of the oesophageal laceration was undertaken.…”
Section: Discussionmentioning
confidence: 87%
“…If undiscovered, an oesophageal perforation inevitably results in mediastinitis and sepsis. The mortality rate of this condition is up to 40% [4,11,12,14,16,18,22]. Cherveniakov et al [6] emphasise the importance of early treatment, and report a delayed diagnosis due to failure to recognise the clinical symptoms in 55% and due to misinterpretation of X-ray findings in another 25% in their series of 147 patients.…”
Section: Discussionmentioning
confidence: 99%
“…Cherveniakov et al [6] emphasise the importance of early treatment, and report a delayed diagnosis due to failure to recognise the clinical symptoms in 55% and due to misinterpretation of X-ray findings in another 25% in their series of 147 patients. Generally, a delay between diagnosis and therapy of more than 24 h has been found to adversely affect the outcome [4,9].…”
Section: Discussionmentioning
confidence: 99%
“…Aniatrogenic cause is found in 55% of the cases of perforation, followed by spontaneous rupture in 15%, foreign body perforation in 14%, and traumatic perforation in 10%. Bladergroen et al (8). reported a total of 127 patients with this disorder, excluding patients with anastomotic leak after esophageal surgery and those in whom perforation occurred in association with carcinoma.…”
Section: Discussionmentioning
confidence: 99%
“…In addition to early treatment, other factors associated with a favorable outcome included traumatic perforation ( 100% survival), foreign-body perforations (94% survival), and iatrogenic causes (80%survival). Spontaneousrupture was associated with the lowest survival (37%) (7)(8)(9). Patients with esophageal perforation frequently present with an antecedent history of vomiting followed by chest pain.…”
Section: Discussionmentioning
confidence: 99%