Diagnosis and surgical therapy of uterine sarkoma

Incidence and Survival of Gynecologic Sarcomas in England

“…In a series including carcinosarcomas, 30 5-year relative survival rates for uterine sarcoma were reported as 64%. This is considerably higher than the 46% 5-year relative survival found in our study (all ages, 1997Y2004), which did not include carcinosarcomas.…”

Cost-Effectiveness Analysis of Morcellation Hysterectomy for Myomas

“…The median age at diagnosis in the United States is 55 years [26]. Unfortunately, there is no reliable tool for the preoperative diagnosis of uterine sarcoma, with the diagnostic sensitivity of preoperative endometrial sampling only approaching 64% [27]. Definitive diagnosis is typically made after hysterectomy via histopathology, although abnormal uterine bleeding, rapidly enlarging pelvic mass, and treatment failure of symptomatic myomas have all been implicated as signs of underlying LMS [28].…”

A Rare Tumor in the Adrenal Region: Neuron-specific Enolase (NSE)-Producing Leiomyosarcoma in an Elderly Hypertensive Patient

“…In the present case, systemic blood pressure was lowered postoperatively although excess of renin, adrenocortical and adrenomedullar hormones was not detected before surgery. Given that more than 30% of uterine leiomyosarcomas were associated with clinical manifestation of hypertension and obesity [41], we cannot completely exclude the possibility that unidentified humoral factors and/or increase of renal sympathetic nerve activity might have been involved in the preoperative hypertension in our case.…”