Diagnosis and Surgical Treatment of Uterine Isthmus Atresia: A Case Report and Review of the Literature

Abstract

Uterine isthmus atresia is a rare M€ ullerian duct anomaly occasionally diagnosed in adolescents with primary amenorrhea and cyclic abdominal pain. A case is presented of a 14-year-old female with monthly cyclic lower abdominal pain of a 2year duration. Magnetic resonance imaging and 3-dimensional ultrasound showed separation of a 10-mm fibrotic tissue between the cervical canal and the endometrial cavity. In an attempt to preserve reproductive ability, an end-to-end anastomosis was laparoscopically performed between the cervical canal and uterine cavity. A platinol stent (WallFlex Biliary RX; Boston Scientific, Boston, MA) was placed by hysteroscopy to avoid stenosis after surgery. Laparoscopic end-to-end anastomosis is proposed to treat congenital uterine isthmus atresia.

Biodegradable Multi-layered Silk Fibroin-PCL Stent for the Management of Cervical Atresia: In Vitro Cytocompatibility and Extracellular Matrix Remodeling In Vivo

“…To eliminate Foley catheters, clinicians employ surgical grafts for needy patients. Usually, reconstruction of the cervical region following canalization and anastomosis has been performed using commercially available Gore-tex, WallFlex, and Nitinol TM . , However, cervical occlusion and revision surgery are reported using non-degradable grafts loaded with cells or growth factors that may pose complications associated with reconstruction and restoration of cervical abnormalities. , …”

“…Usually, reconstruction of the cervical region following canalization and anastomosis has been performed using commercially available Gore-tex, WallFlex, and Nitinol TM . 52,53 However, cervical occlusion and revision surgery are reported using non-degradable grafts loaded with cells or growth factors that may pose complications associated with reconstruction and restoration of cervical abnormalities. 54,55 Herein, the material selection and associated design can heavily influence cervical stent performance and efficacy while considering biodegradable polymer grafts for this application.…”