Diagnosis and treatment of acute phlegmonous gastritis

Yang, Huiling; Yan, Zhiqiang; Chen, Jiaju; Xie, Hongyu; Wang, Haibin; Wang, Qian

doi:10.1097/md.0000000000010629

Cited by 22 publications

(47 citation statements)

References 17 publications

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“…Furthermore, various routes of infection, including direct and hematogenous infection of the lumen, have been implicated and termed primary and secondary forms of PG, respectively [11,12]. Lastly, there are localized and diffuse forms of the disease with the latter form demonstrating significantly higher mortality rates (10% vs. 54%) [13,14]. Any mucosal injury can provide a route for bacterial penetration, and in this case, a background state of immunosuppression likely predisposed the patient to a fulminant bacterial infection [4].…”

Section: Discussionmentioning

confidence: 99%

Phlegmonous gastritis complicated by abdominal compartment syndrome: a case report

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Tabari

2021

BMC Surg

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Background Phlegmonous gastritis (PG) is a rare, suppurative bacterial infection of the gastric wall, which may rapidly evolve into fatal septicemia. The etiology and pathogenesis are poorly understood; however, multiple risk factors have been cited in current literature. Most cases have been diagnosed at autopsy, and occasionally at laparotomy, as the clinical presentation is often variable. Case presentation We report a case of a 67-year-old male presenting with intractable nausea, vomiting, and epigastric pain following an uneventful upper gastrointestinal (GI) endoscopy. Diagnostic workup including contrast tomography (CT) and endoscopic assessment was in keeping with PG. This was subsequently followed by development of abdominal compartment syndrome (ACS) and clinical deterioration necessitating surgical resection of the stomach. Conclusion This case emphasizes the importance of early diagnosis of this potentially fatal infection that can follow endoscopic procedures and illustrates ACS and septic shock as serious complications. There is currently no consensus on the proper management of PG; however, in this case, a combination of surgery and antibiotics provided a favourable outcome. Limited number of cases of PG have been reported in literature, and to our knowledge, this is the first reported case of PG with subsequent ACS as an acute complication.

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Section: Discussionmentioning

confidence: 99%

Phlegmonous gastritis complicated by abdominal compartment syndrome: a case report

Modares

Tabari

2021

BMC Surg

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“…Diffuse PG has higher mortality rates (10 vs 54%). 3,7 This case was classified as primary and diffuse.…”

Section: Discussionmentioning

confidence: 99%

A Patient With Good Syndrome Complicated With Phlegmonous Gastritis

et al. 2019

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Phlegmonous gastritis (PG) is a rare and severe infection, with less than 500 cases reported. Similarly, Good syndrome represents a rare adult-onset immunodeficiency with a prevalence of 1 in 500,000 people. We present the first case of a patient with Good syndrome complicated with PG. Given that up to 50% of patients with PG do not have an identified risk factor, underlying immunodeficiencies should be conscientiously investigated.

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“…3 ). This type can cause gastric cavity expansion and gastric wall perforation [ 10 ]. The localized type is associated with a lower mortality rate (10%) than the diffuse type (54%) [ 1 , 2 ].…”

Section: Discussionmentioning

confidence: 99%

Sepsis caused by acute phlegmonous gastritis based on a group A Streptococcus

Ramphal

Mus

Nuytinck

et al. 2018

Journal of Surgical Case Reports

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We present a case of 45-year-old male with acute phlegmonous gastritis (APG) based on a hemolytic group A Streptococcus. APG is a rare and often a potentially fatal disease, which is characterized by a severe bacterial infection of the gastric wall. Because APG is a rapidly progressive disease, it comes with high mortality rates. Patients with an early diagnosis may undergo successful treatment and have a survival benefit. As soon as the diagnosis of APG is suspected, aggressive and adequate antibiotic treatment in combination with surgical intervention should be considered.

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Diagnosis and treatment of acute phlegmonous gastritis

Abstract: Acute PG is a rare infection of the gastric wall especially after antibiotic treatment. Given the fast progression of this disease, early recognition and immediate action are crucial to achieve positive outcomes.

Cited by 22 publications

References 17 publications

Phlegmonous gastritis complicated by abdominal compartment syndrome: a case report

Phlegmonous gastritis complicated by abdominal compartment syndrome: a case report

A Patient With Good Syndrome Complicated With Phlegmonous Gastritis

Sepsis caused by acute phlegmonous gastritis based on a group A Streptococcus

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