Diagnosis and Treatment of Anxiety in the Aging Woman

Siegel, Andrew M.; Mathews, Sarah B.

doi:10.1007/s11920-015-0636-3

Cited by 27 publications

(25 citation statements)

References 56 publications

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“…Recent research has attempted to describe female’s heightened response to stressors by exploring the effects of stress during peri- and post-menopausal periods, as these represent windows of vulnerability for women to develop mood disorders [ 294 - 298 ]. Specifically, women are 2 to 3 times more likely to experience a first episode of depression during the peri-menopausal period [ 299 , 300 ].…”

Section: Sex Differences In Aging and Stress Resiliencementioning

confidence: 99%

Neurobiological Mechanisms of Stress Resilience and Implications for the Aged Population

et al. 2018

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Background:Stress is a common reaction to an environmental adversity, but a dysregulation of the stress response can lead to psychiatric illnesses such as major depressive disorder (MDD), post-traumatic stress disorder (PTSD), and anxi-ety disorders. Yet, not all individuals exposed to stress will develop psychiatric disorders; those with enhanced stress resili-ence mechanisms have the ability to adapt successfully to stress without developing persistent psychopathology. Notably, the potential to enhance stress resilience in at-risk populations may prevent the onset of stress-induced psychiatric disorders. This novel idea has prompted a number of studies probing the mechanisms of stress resilience and how it can be manipulat-ed.Methods: Here, we review the neurobiological factors underlying stress resilience, with particular focus on the serotoninergic (5-HT), glutamatergic, and γ-Aminobutyric acid (GABA) systems, as well as the hy-pothalamic-pituitary axis (HPA) in rodents and in humans. Finally, we discuss stress resiliency in the context of aging, as the likelihood of mood disorders increases in older adults.Results: Interestingly, increased resiliency has been shown to slow aging and improved overall health and quality of life. Research in the neurobiology of stress resilience, particularly throughout the aging process, is a nascent, yet, burgeoning field.Conclusion: Overall, we consider the possible methods that may be used to induce resilient phenotypes, prophylactically in at-risk populations, such as in military personnel or in older MDD patients. Research in the mechanisms of stress resilience may not only elucidate novel targets for antidepressant treatments, but also provide novel insight about how to prevent these debilitating disorders from developing.

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Section: Sex Differences In Aging and Stress Resiliencementioning

confidence: 99%

Neurobiological Mechanisms of Stress Resilience and Implications for the Aged Population

et al. 2018

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“…Among perimenopausal women, treatment options for anxiety may include pharmacotherapy, hormone therapy (HT), or psychotherapy (153). In terms of pharmacotherapy, most research has focused on depressive symptoms, not anxiety.…”

Section: Treatment and Outcomesmentioning

confidence: 99%

Anxiety Disorders Among Women: A Female Lifespan Approach

Hantsoo

Epperson

2017

FOC

114

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Anxiety symptoms may present differently between women and men, and at different points in the female lifespan. The female lifespan includes distinct epochs of hormonal function, including puberty, the premenstruum, in some women pregnancy or postpartum, and the menopausal transition. These stages give rise to important treatment considerations when treating anxiety in women. When making assessments, the clinician should consider reproductive events and hormonal status, as well as sex differences in anxiety presentation. This review is structured to: 1) Define major epochs of the female lifespan, 2) Provide a brief summary of the major anxiety disorders, with a focus on prevalence and presentation in the context of sex differences and at points in the female lifespan, 3) Describe potential biopsychosocial underpinnings of anxiety disorders among women, 4) Provide guidelines for assessment and differential diagnosis, and 5) Describe treatment options with attention to reproductive events such as pregnancy.

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“…The most common symptoms include tachycardia, sleep problems, sweating, dizziness, gastrointestinal disorders, and nausea. 11,12 Thus, depression produces a delay in therapeutic response and worsens prognosis in patients with anxiety disorders, 10 most likely leading to suicide attempts in geriatric patients. 13 All of these factors impair QOL, favoring social isolation and the appearance of severe cases of clinical diseases.…”

Section: Introductionmentioning

confidence: 99%

The effects of physical activity on anxiety, depression, and quality of life in elderly people living in the community

Oliveira

Souza

Rodrigues

et al. 2019

Trends Psychiatry Psychother.

220

124

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Introduction: Health problems may negatively affect the psychological and physical aspects of life, influencing the quality of life of older adults. The objective of this study was to analyze the effects of physical activity on quality of life, anxiety, and depression in the elderly population. Methods: We performed a cross-sectional study of 200 elderly people of both genders. Subjects were divided into two groups: one with 100 senior citizens engaged in physical activities in a social center for the elderly; and another composed of 100 subjects who lived in the community but were not engaged in physical activities. The instruments used to assess physical activities, quality of life, and anxiety and depression were, respectively: the modified Baecke questionnaire; the 36-Item Short Form Health Survey (SF-36); and the Hospital Anxiety and Depression Scale (HADS). The data were analyzed using the Student's t test, Pearson's r, and analysis of variance (ANOVA), with odds ratio and a 5% significance level (p<0.05). Results: We observed that the active group showed higher scores of physical activity and quality of life. Conversely, the sedentary group revealed higher scores of anxiety and depression. Data assessment revealed a strong correlation between the domains quality of life, level of vitality, and mental health (r=0.77). The prevalence ratio showed that physical activity is a protective factor against anxiety and depression in the elderly. Conclusion: The findings suggest a correlation between low levels of physical activity and symptoms of anxiety and depression in the elderly living in the community.

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Diagnosis and Treatment of Anxiety in the Aging Woman

Cited by 27 publications

References 56 publications

Neurobiological Mechanisms of Stress Resilience and Implications for the Aged Population

Neurobiological Mechanisms of Stress Resilience and Implications for the Aged Population

Anxiety Disorders Among Women: A Female Lifespan Approach

The effects of physical activity on anxiety, depression, and quality of life in elderly people living in the community

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