Diagnosis and treatment of early lung cancer

McLellan, Rachel; Marshall, Henry; Dent, Annette; Bowman, Rayleen V.; Yang, Ian A.; Fong, Kwun M.

doi:10.31128/ajgp-11-19-5148

Cited by 8 publications

(8 citation statements)

References 22 publications

(22 reference statements)

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“…In addition, traditional tumour biomarkers have a low sensitivity for early diagnoses due to the low tumour burden released into peripheral circulation in early-stage lung cancer. 27 We also observed the diagnostic value of these two circRNAs compared with CEA, CYFRA21-1, and SCC. The ROC curves showed that the AUC values of hsa_circ_101555 and hsa_circ_008068 were excellent compared with those of traditional tumour markers for the diagnosis of early LUAD.…”

Section: Discussionmentioning

confidence: 69%

Circular RNAs Hsa_circ_101555 and Hsa_circ_008068 as Diagnostic Biomarkers for Early-Stage Lung Adenocarcinoma

Cao

et al. 2022

IJGM

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Section: Discussionmentioning

confidence: 69%

Circular RNAs Hsa_circ_101555 and Hsa_circ_008068 as Diagnostic Biomarkers for Early-Stage Lung Adenocarcinoma

Cao

et al. 2022

IJGM

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“…In recent years, non-tracheal intubation anesthesia has developed rapidly, and preservation of the patient's selfbreathing during thoracoscopic surgery can effectively avoid the occurrence of airway trauma and postoperative complications caused by tracheal intubation (20,21). In our team's previous study (4), performing VATS pneumonectomy under non-intubation anesthesia reduced the intraoperative blood loss, postoperative drainage, postoperative white blood cell and neutrophil proportions, and reduced hospitalization costs. It has been reported that endotracheal intubation can cause sympathetic nerve excitation (22), which leads to increased blood pressure, whereas the non-endotracheal intubation method avoids the pressure effect, and hemodynamics remain more stable.…”

Section: Discussionmentioning

confidence: 96%

“…At present, the preferred method for the early diagnosis and treatment of pulmonary nodules is video-assisted thoracoscopic surgery (VATS) (3). Thoracic pneumonectomy is performed under conventional tracheal intubation anesthesia, but tracheal intubation is an invasive procedure that can damage the trachea, cause postoperative discomfort in the throat of the patient, and also cause damage to the non-ventilated lung (4). Moreover, it requires a large dose of anesthetics.…”

Section: Introductionmentioning

confidence: 99%

Comparison of two preoperative positioning techniques and unpositioning methods in non-intubated video-assisted thoracoscopic surgery

Yu¹,

Liu²,

Bo³

et al. 2022

J Thorac Dis

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Background: Using the non-intubated video-assisted thoracoscopic surgery (VATS) approach for small pulmonary nodules (SPNs) can accelerate patients' postoperative recovery. However, locating the SPNs intraoperatively by palpation can be difficult for thoracic surgeons. The advantages of using different preoperative positioning materials are different, especially for pulmonary-nodule-location-needle (P-N-L-N) and the microcoil. This retrospective study analyzed the advantages of two preoperative positioning techniques for VATS under non-intubation anesthesia.Methods: The data were collected for a total of 150 patients with pulmonary nodules who underwent nonintubated VATS at the First People's Hospital of Yunnan Province from January 2018 to January 2021. The patients were divided into a preoperative positioning group (including a P-N-L-N group and microcoil group) and an unlocalized group. These included patients were all compliant with surgical guidelines and were suitable for preoperative localization. Their intraoperative and postoperative indicators were compared, and among these indicators, the operative time, number of postoperative drainage days, postoperative total drainage volume, postoperative discharge time was efficacy group and the intraoperative blood loss was safety group.Results: Preoperative localization helped surgeons to explore nodules faster intraoperatively and remove SPNs precisely under non-intubated VATS. But the advantages of using different preoperative positioning materials are different. Positioning with either microcoil or P-N-L-N resulted in less operation time (P

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“…The lung is an important organ of the human respiratory system, and lung tumor is also directly related to human health. Early surgical planning and treatment can improve the cure rate and increase the survival rate of patients [ 2 , 3 ]. Computer-aided accurate segmentation can effectively assist doctors in surgery planning and treatment decisions [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

An Automatic Segmentation Method for Lung Tumor Based on Improved Region Growing Algorithm

Wang

2022

Diagnostics

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In medical image processing, accurate segmentation of lung tumors is very important. Computer-aided accurate segmentation can effectively assist doctors in surgery planning and treatment decisions. Although the accurate segmentation results of lung tumors can provide a reliable basis for clinical treatment, the key to obtaining accurate segmentation results is how to improve the segmentation performance of the algorithm. We propose an automatic segmentation method for lung tumors based on an improved region growing algorithm, which uses the prior information on lung tumors to achieve an automatic selection of the initial seed point. The proposed method includes a seed point expansion mechanism and an automatic threshold update mechanism and takes the combination of multiple segmentation results as the final segmentation result. In the lung image database consortium (LIDC-IDRI) dataset, we designed 10 experiments to test the proposed method and compare it with 4 popular segmentation methods. The experimental results show that the average dice coefficient obtained by the proposed method is 0.936 ± 0.027, and the average Jaccard distance is 0.114 ± 0.049. The average dice coefficient obtained by the proposed method is 0.107, 0.053, 0.040, and 0.156, higher than that of the other four methods, respectively. This study proves that the proposed method can automatically segment lung tumors in CT slices and has suitable segmentation performance.

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Diagnosis and treatment of early lung cancer

Abstract: BackgroundLung cancer is the leading cause of cancer death in Australia. Recently there have been unparalleled advances in the screening and management of lung cancer.

Cited by 8 publications

References 22 publications

Circular RNAs Hsa_circ_101555 and Hsa_circ_008068 as Diagnostic Biomarkers for Early-Stage Lung Adenocarcinoma

Circular RNAs Hsa_circ_101555 and Hsa_circ_008068 as Diagnostic Biomarkers for Early-Stage Lung Adenocarcinoma

Comparison of two preoperative positioning techniques and unpositioning methods in non-intubated video-assisted thoracoscopic surgery

An Automatic Segmentation Method for Lung Tumor Based on Improved Region Growing Algorithm

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