Diagnosis and treatment of pyogranulomatous panniculitis due to Mycobacterium smegmatis in cats

Abstract

Four cats with extensive pyogranulomatous panniculitis and dermatitis due to Mycobacterium smegmatis were evaluated over an eight‐month period. All were treated initially with doxycycline (50 mg per cat every eight to 12 hours) for several weeks, then subjected to radical surgical excision of infected tissues. Reconstructive surgery utilising advancement flaps was required to close wounds without undue tension. Postoperatively, the cats received parenteral gentamicin (2 mg/kg every eight hours) for three to five days, followed by orally administered ciprofloxacin (62.5 mg per cat every eight hours or 125 mg per cat every 12 hours) for three to six months. Infection was eradicated in all the cats, with no signs of recurrence 15 to 23 months after surgery.

Repair of an axillary non‐healing gunshot wound with MRSA strain infection in a cat

“…Removal of a tissue wedge for culture is preferable to bacteriology swabs that may not penetrate the deeper tissue layers where the resistant bacteria are likely to proliferate. Unusual pathogens have been reported to affect the axillary area and should be excluded by means of special staining and culture techniques (Malik and others 1994). …”

Infectious Diseases

“…53,230 This tremendous variation has an impact on diagnostics, therapeutics, and vaccine development. Some of these mutations may lead to changes in virulence or antigenicity.…”

“…The most common presentation is localized infection in healthy cats, most typically chronic panniculitis 72 ; there have been occasional reports of pneumonia caused by RGM. 3 In Australia, organisms from the M. smegmatis group account for most feline cases, 53,57 while in the United States, most cases are caused by members of the M. fortuitum group. 17 Other countries with reported cases include the United States, 49 Canada, 17,74 New Zealand, 17 France, 68 Finland, 1 the Netherlands, 43 and Switzerland.…”

“…7 Both outdoor and exclusively indoor cats are at risk of infection. 33,53 Specific GI signs occur less commonly in cats than in dogs. Breed predilection is not consistently described, but Persian cats were predisposed in one report.…”

Idiopathic sterile pyogranuloma in three domestic cats

“…Generalised PI has been extensively described in the veterinary literature, particularly in cases of feline infectious peritonitis (FIP) ( Weiss & Scott , Kipar et al . ). Cutaneous, subcutaneous and, more rarely, systemic PI in cats is mainly associated with mycobacteria and fungal infections ( Malik et al . , , , Brömel & Sykes , Baral et al . ) with sporadic implication of Actinomyces, Nocardia, Rhodococcus, Streptomyces, Francisella, Bartonella and Leishmania ( Patel ; Valentine et al . ; Malik et al . ; Farias et al ., ; Santero et al . ; Sharman et al . ; Varanat et al . ; Traslavina et al . ). Idiopathic sterile pyogranulomatous dermatitis has also been described in cats ( Scott et al . ).…”