Diagnosis and treatment of submucous myoma of the uterus with interventional ultrasound

Abstract

The value of interventional ultrasound in the diagnosis and treatment of submucous myoma of the uterus was assessed to study the ultrasonographic features of modified sonohysterography for submucous polyp of uterus. A total of 25 patients diagnosed preliminarily as submucous myoma of the uterus via conventional ultrasound examination from June 2014 to December 2016 were enrolled in the study. The diagnosis was made via the comprehensive analysis of ultrasound-guided modified SHG, followed by ultrasound-guided needle biopsy and sclerotherapy of tumor. After modified SHG and ultrasound-guided needle biopsy, 96% (24/25) cases were confirmed pathologically as submucous myoma of the uterus. After treatment, the maximum diameter of myoma in patients with submucous myoma of uterus was significantly different, and the volume of myoma was significantly reduced. After treatment, the clinical symptoms of patients with submucous myoma of the uterus were obviously improved compared to before treatment (P<0.05). It was found in the follow-up after treatment that a small number of patients suffered from mild abdominal pain, increased secretion, slight vaginal bleeding, cold sweat, pale complexion, dizziness and other symptoms, which, however, disappeared after treatment for about 1 week. The score of 36 item Short-Form Health Survey Questionnaire of patients with submucous myoma of the uterus was significantly different before and after treatment (P<0.05). Interventional ultrasonography can effectively diagnose the submucous myoma of uterus. The treatment of submucous myoma of uterus with ultrasound-guided intratumor injection of lauromacrogol is characterized by simple operation, which can effectively reduce the tumor diameter and volume, improve the blood flow in patients, reduce the postoperative adverse reactions and alleviate the patient's pain, so it is a new type of minimally invasive treatment method of submucous myoma of the uterus, and it is worthy of clinical promotion and application.

A Case Report of the Largest Submucosal Uterine Leiomyoma Removed by Single-Session Hysteroscopic Myomectomy in the Caribbean

“…The incidence of submucosal leiomyomas of the uterus is approximately 5-10% [5]. Although less common than subserosal and intramural leiomyomas, submucosal myomas are associated with greater morbidity, including dysmenorrhea, menorrhagia, symptomatic anemia requiring blood transfusions, infertility, and an increased risk of early pregnancy complications [5]. Depending on the severity of symptoms, treatment options may be medical or surgical.…”

Predicting Endometriosis Onset Using Machine Learning Algorithms

“…The machine learning models have also identi ed Acetaminophen (R_ACETAMINOPHEN), Megestrol acetate (R_MEGESTROL_ACETATE) & Lidocaine hcl (R_LIDOCAINE_HCL) drugs as the strong predictors of endometriosis, as these drugs are often prescribed as analgesics, birth control & treatment of endometrial cancer and to numb the skin/muscles respectively. Furthermore, features such as 'submucous leiomyoma of uterus (D_D25_0)' and 'hypertrophy of uterus (D_N85_2)' are signi cant predictors [49,50] in the disease onset; however, more clinical research is needed to support this statement, as these conditions have similar symptoms, but patients are less likely to develop endometriosis [51].…”

Karakteristik Pasien Leiomyoma Uteri Pada Masyarakat Pesisir Di Lumajang Tahun 2019-2021

“…Leiomyoma uteri omerupakan osalah osatu masalah kesehatan oreproduksi perempuan yang omemiliki opengaruh osignifikan terhadap omorbiditas odan okualitas hidup opasien (2). Studi klinis telah mengkonfirmasi bahwa leiomyoma uteri dapat menyebabkan kemandulan dan anemia, dan bahkan mengancam nyawa pada kasus yang parah (3). Penyakit ini di Indonesia, merupakan kanker tersering kedua yang terjadi pada perempuan setelah kanker serviks (4).…”