Diagnosis of a biliary cystadenoma demonstrating communication with the biliary system by MRI using a hepatocyte-specific contrast agent

Abstract

ABSTRACT. Biliary cystadenomas are predominately benign tumours that have a low malignant potential. We present a case of a 30-year-old female with a histopathological confirmation of a biliary cystadenoma following resection. The diagnosis was made preoperatively by MRI using the hepatocyte-specific contrast agent gadobenate dimeglumine [Gd-BOPTA (MultiHance; Bracco Diagnostics Inc., Princeton, NJ)]. At the biliary excretory phase, delayed phase images demonstrated communication between the multilocular cystic mass and the biliary tree, which helped to confirm the diagnosis of biliary cystadenoma. This highlights the beneficial use of hepatocyte-specific agents for their dual function as an extracellular agent and a hepatobiliary agent.

Cystic Neoplasms of the Liver: Biliary Cystadenoma and Cystadenocarcinoma

“…(54) Further studies will be required to establish the relative additional utility of diffusion weighted MR. MRCP can also be helpful in that it can demonstrate cyst communication with the biliary tree as well as identify internal septations. (52, 55) MRCP can better visualize the biliary tree proximal to an obstruction, unlike ERCP. (52) ERCP is uncommonly utilized for BCT, but in select circumstances may be helpful in obtaining tissue samples, identifying biliary tree communications, and extrahepatic BCTs.…”

Biliary cystadenoma a case report

“…14 Diagnosis of BCA can be made with USG and CT scan on ultrasound, the cystic nature of the lesion with multiple loculi, septations, and internal echoes, with papillary projections is typical, cyst wall enhancement in CECT scan can delineate further anatomic details the differential diagnosis are Simple liver cyst, Hydatid cyst, haemorrhagic cyst and Poly cystic disease of liver. 3,[14][15][16][17] An irregular wall thickening, mural nodule or presence of papillary projection indicate possibility of malignancy. 3,16,18 A preoperative cyst fluid aspiration or core needle biopsy for diagnosis has been advocated in studies but diagnostic value is controversial and not accurate.…”

Tumores hepáticos incomuns: ensaio iconográfico - Parte 1

“…Biliary cystadenomas are uncommon and represent less than 5% of all uni- or multilocular cysts of biliary origin ( 10 ) . Generally, most of these lesions are intrahepatic (85% of cases), with diameter ranging from 1.5 cm to 35 cm and predilection for the right liver lobe ( 9 ) .…”