Diagnosis of active tuberculosis and latent tuberculosis infection based on Raman spectroscopy and surface-enhanced Raman spectroscopy

Kaewseekhao, Benjawan; Nuntawong, Noppadon; Eiamchai, Pitak; Roytrakul, Sittiruk; Reechaipichitkul, Wipa; Faksri, Kiatichai

doi:10.1016/j.tube.2020.101916

Cited by 29 publications

(21 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Active tuberculosis and latent tuberculous infection can be detected with both Raman spectroscopy and SERS. Kaewseekhao et al [148] developed a protocol based on Raman spectroscopy to diagnose and distinguish between active and latent tuberculosis with an accuracy of 91.15%. Furthermore, SERS can distinguish between all TB-infection categories with 100% sensitivity and specificity.…”

Section: Biological Applicationsmentioning

confidence: 99%

A Comprehensive Review on Raman Spectroscopy Applications

et al. 2021

View full text Add to dashboard Cite

Raman spectroscopy is a very powerful tool for material analysis, allowing for exploring the properties of a wide range of different materials. Since its discovery, Raman spectroscopy has been used to investigate several features of materials such carbonaceous and inorganic properties, providing useful information on their phases, functions, and defects. Furthermore, techniques such as surface and tip enhanced Raman spectroscopy have extended the field of application of Raman analysis to biological and analytical fields. Additionally, the robustness and versatility of Raman instrumentations represent a promising solution for performing on-field analysis for a wide range of materials. Recognizing the many hot applications of Raman spectroscopy, we herein overview the main and more recent applications for the investigation of a wide range of materials, such as carbonaceous and biological materials. We also provide a brief but exhaustive theoretical background of Raman spectroscopy, also providing deep insight into the analytical achievements.

show abstract

Section: Biological Applicationsmentioning

confidence: 99%

A Comprehensive Review on Raman Spectroscopy Applications

et al. 2021

View full text Add to dashboard Cite

show abstract

“…In a previous study, Raman spectroscopy was reported as promising, rapid and accurate technique for identification of clinically relevant Mycobacterium species [68]. Conclusive research in larger sample size is required to implement this technique in diagnosis of TB [69].…”

Section: (C) Next-generation Sequencing (Ngs)mentioning

confidence: 99%

Diagnostic Modalities of Tuberculosis- Then and Now

Tayal

Sethi

Jain

2022

AJMAH

View full text Add to dashboard Cite

Tuberculosis is one of the most ancient diseases known to affect humans and according to WHO remains major cause of death after HIV/AIDS. It remains a global public health problem due to increasing number of undiagnosed and drug resistant cases. Early diagnosis and immediate initiation of treatment is crucial to prevent the extensive spread of this deadly disease. Nowadays advancements in molecular based test imparted better and rapid diagnosis of TB. Several commonly used methods to screen and diagnose TB are clinical, immunological, microscopy, radiography, and bacterial culture. Molecular diagnostic methods including loop-mediated isothermal amplification (LAMP), line probe assays (LPA), GeneXpert, whole genome sequencing (WGS) etc have been employed to diagnose and characterize TB. Here, we reviewed use of these currently available and other future promising diagnostic methods along with their sensitivity, specificity, advantage and disadvantage of each method. Although new diagnostic methods have been developed, they require extensive amount of studies to validate their confirmatory role in the diagnosis of TB. There is increased requirement for biomarker discovery, validation and translation into clinical tools. High-burden countries will need to improve their efficiency of health care delivery and ensure better uptake of new technologies.

show abstract

“…The technique utilizes the principle of Raman scattering, creates specific molecular fingerprints when excited with light of certain wavelength on various bacteria. The turnaround time by RS is very short (Kaewseekhao et al, 2020;Muhlig et al, 2016;Stockel et al, 2017).…”

Section: Raman Spectroscopy (Rs)mentioning

confidence: 99%

Tuberculosis Diagnostics, a journey from the past Experiences to the Future Directions, Review

Moorthy

Bhaskar

Shivakumar³

et al. 2022

AGJSR

View full text Add to dashboard Cite

Purpose: Tuberculosis caused by Mycobacterium tuberculosis is believed to have been acquired from animals especially cattle. Not one country across the globe is spared of the disease. The infection gets established through respiratory system where they are either latent or active. Depending upon the immune status or coexisting infection or other health disorders the infection may be either contained within the lungs or spread to other parts of the body. Hence rapid and accurate diagnosis is needed to initiate appropriate treatment. Sputum studies are being followed for diagnosis of tuberculosis but has few disadvantages. Xpert MTB/RIF, an automated, molecular test has been in vogue now. Biomarkers such as complete blood count, inflammatory and oxidative stress markers are being measured. Recently epigenetic markers like microRNA are being analyzed to differentiate the various presentations of tuberculosis. This review has been undertaken to understand the various diagnostic strategies being followed from the old times to the newer novel techniques. Methods: The narrative review was undertaken by searching the original and review articles in the past 20 years. The articles were obtained by searching through various search engines. Since this was a review article ethics committee approval was not required. Results: The traditional methods have inherent limitations of high expertise, prolonged procedure, not cost effective and require good infrastructure. Newer methods are found to be sensitive, specific, reproducible and cost effective. But require validation to be implemented into routine use. Conclusions: Validating the new markers such as epigenetic markers – microRNAs should pave way for diagnosis and management of pulmonary TB, extrapulmonary TB, TB in HIV infected individuals, pregnant women and children. This could serve as a finger-print sort of diagnosis once validated on large scale community-based studies.

show abstract

Diagnosis of active tuberculosis and latent tuberculosis infection based on Raman spectroscopy and surface-enhanced Raman spectroscopy

Cited by 29 publications

References 24 publications

A Comprehensive Review on Raman Spectroscopy Applications

A Comprehensive Review on Raman Spectroscopy Applications

Diagnostic Modalities of Tuberculosis- Then and Now

Tuberculosis Diagnostics, a journey from the past Experiences to the Future Directions, Review

Contact Info

Product

Resources

About