Diagnosis of acute toxoplasmosis by IgG avidity method in pregnant women referred to health centers in south-eastern Iran

Rahmati-Balaghaleh, Mansour; Farash, Bibi Razieh Hosseini; Zarean, Mehdi; Hatami-Pourdehno, Saeed; Jarahi, Lida; Sharifi, Yousef; Ahmadi, Omid; Shamsian, Seyed Aliakbar; Moghaddas, Elham; Shahri, Seyed Mohammad Hashemi

doi:10.1007/s12639-019-01120-8

Cited by 10 publications

(5 citation statements)

References 12 publications

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“…The seropositivity of the present study is consistent with that in the previous studies conducted on 375 blood donors (25%) and 119 healthy individuals (23%) in Zahedan, Iran [ 9 , 11 ]. The seropositivity to Toxoplasma gondii infection in this study is lower than that in 221 pregnant women (30.8%), 119 hemodialysis patients (44.5%), and 154 patients undergoing chemotherapy (39.4%) in Zahedan, southeast Iran [ 10 – 12 ]. Furthermore, the seroprevalence obtained from the present study is lower than that reported from Iran's neighbor countries, including Qatar (29.8%), Pakistan (29.48%), and Turkey (31.9%) [ 15 – 17 ].…”

Section: Discussionmentioning

confidence: 54%

“…In the southeast of Iran, Sistan and Baluchistan province, Zahedan city, several studies have been conducted on seroprevalence of toxoplasmosis in the population of blood donors [ 9 ], pregnant mothers [ 10 ], hemodialysis patients [ 11 ], and patients undergoing chemotherapy for malignancies [ 12 ]. The seroprevalence of toxoplasmosis varies in healthy individuals in different provinces of Iran.…”

Section: Introductionmentioning

confidence: 99%

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Seroprevalence and Risk Factors Associated with Toxoplasma gondii Infection in the Population Referred to Rural and Urban Health Care Centers in Zahedan, Primary Referral Level, in Southeastern Iran

Khabisi

Almasi

Zadeh

2022

Journal of Parasitology Research

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Introduction. Toxoplasmosis is one of the protozoan diseases caused by Toxoplasma gondii. This study is aimed at evaluating the seroprevalence and associated risk factors of Toxoplasma gondii infection in the population referred to rural and urban health care centers in Zahedan, southeast Iran. Methods. A total of 1,324 blood samples of patients referred to the health care centers were evaluated using the IgG Toxoplasma ELISA Kit, between October 2019 and August 2021. The obtained data were analyzed through univariable and multivariable regression models. Results. The seropositivity of Toxoplasma gondii infection was obtained at 18.8%. In the multivariable logistic regression model, risk factors including age group of 11-30 ( OR = 3.25 , 95% CI: 1.29-7.06), urban residency ( OR = 4.36 , 95% CI: 2.9-6.3), students ( OR = 3.76 , 95% CI: 1.88-4.53), and contact with cat ( OR = 7.67 , 95% CI: 4.76-12.36) were significantly associated with seropositivity to Toxoplasma gondii infection. Moreover, consumption of washed vegetables with salt or detergents decreases ( OR = 0.14 , 95% CI: 0.09-0.23) the risk of Toxoplasma gondii infection. According to the results of the multivariable logistic regression, no significant association was observed between seropositivity to Toxoplasma gondii and other risk factors. Conclusion. The results of this study indicated significant seropositivity to Toxoplasma gondii infection in the population referred to rural and urban health care centers in Zahedan, Iran. Therefore, health programs should be considered for raising awareness regarding the risk factors for Toxoplasma gondii infection in this region.

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Section: Discussionmentioning

confidence: 54%

Section: Introductionmentioning

confidence: 99%

Seroprevalence and Risk Factors Associated with Toxoplasma gondii Infection in the Population Referred to Rural and Urban Health Care Centers in Zahedan, Primary Referral Level, in Southeastern Iran

Khabisi

Almasi

Zadeh

2022

Journal of Parasitology Research

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“…Serum samples were screened using ready-made ELISA kits (Abcam, USA), and an ELISA plate reader (Bio-Rad, Hercules, CA). The optical density was measured at 450 nm and the antibody (IgM and IgG) titre for each sample was calculated [16] . Following the manufacture's protocol, a Toxoplasma IgM titre <0.8 was considered negative; 0.8-1.0 was considered equivocal; and > 1 was considered positive.…”

Section: Detection Of Anti-toxoplasma Igm and Igg In Patients' Seramentioning

confidence: 99%

The impact of H. pylori and/or T. gondii infection on recurrence of gastritis and gastric ulcer

Elawamy

Ghazy

Haydara

et al. 2021

Parasitologists United Journal

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“…In Iran, previous studies have reported the incidence and prevalence of congenital infections among pregnant women (24)(25)(26)(27)(28). Thus, it is imperative for TRC screening among women during pregnancy in the region, which is useful for early detection and proper management (diagnosis, treatment, and follow-up); this can further prevent complications among newborns.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Toxoplasma gondii, Rubella, and Cytomegalovirus Antibodies in Pregnant Women in Yazd Province, Iran

Ahmadi,

Sadeghinasab,

Siyadatpanah

et al. 2023

Avicenna J Clin Microbiol Infect

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Background: TRC (Toxoplasma gondii, rubella virus, and cytomegalovirus [CMV]) infections during pregnancy can lead to serious sequelae in the uterine fetus. Prenatal testing, which includes screening and diagnosis of antibodies to TRC infections, is one of the most important aspects of prenatal care recommended during pregnancy. The aim of the present study was to determine the seroprevalence of TRC infections in pregnant women who attended the antenatal clinic in Yazd province in central Iran. Methods: For this purpose, 8355 sera samples were obtained from pregnant women attending the central laboratory of Yazd province in central Iran and subjected to screening for immunoglobulin G (IgG) and IgM antibodies against TRC using the enzyme-linked immunosorbent assay method. Of these, 4,245, 2,190, and 1,920 pregnant women were screened for anti-Toxoplasma, rubella, and CMV, IgG, and IgM antibodies, respectively. Results: The results revealed that 77.4% (1695/2190) and 78.1% (1500/1920) were positive for anti-rubella and anti-CMV IgG antibodies, and n.o seropositive was detected for anti-rubella and -CMV IgM antibodies. For anti-Toxoplasma antibodies, 20.85% (885/4245), 9.54% (405/4245), and 12.01% (510/4245) were positive for IgG, IgM, and both IgG-IgM antibodies, respectively. In addition, our findings showed the high prevalence of chronic TRC infections and a low recently acquired Toxoplasma infection in pregnant women. Conclusion: Our findings confirmed the high prevalence of chronic TRC infections and a low recently acquired Toxoplasma infection in pregnant women. Hence, observing personal behavioral practices (the source of infection and hygienic measures) are recommended to women at reproductive-age in general and seronegative pregnant women in particular.

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Diagnosis of acute toxoplasmosis by IgG avidity method in pregnant women referred to health centers in south-eastern Iran

Cited by 10 publications

References 12 publications

Seroprevalence and Risk Factors Associated with Toxoplasma gondii Infection in the Population Referred to Rural and Urban Health Care Centers in Zahedan, Primary Referral Level, in Southeastern Iran

Seroprevalence and Risk Factors Associated with Toxoplasma gondii Infection in the Population Referred to Rural and Urban Health Care Centers in Zahedan, Primary Referral Level, in Southeastern Iran

The impact of H. pylori and/or T. gondii infection on recurrence of gastritis and gastric ulcer

Frequency of Toxoplasma gondii, Rubella, and Cytomegalovirus Antibodies in Pregnant Women in Yazd Province, Iran

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