Diagnosis of atherosclerosis in human carotid artery by FT-Raman spectroscopy: Principal Components Analysis algorithm

Nogueira, Grazielle Vilela; Silveira, Landulfo; Martin, Aírton Abrahão; Zângaro, Renato Amaro; Pacheco, Marcos Tadeu Tavares; Chavantes, Maria Cristina; Zampieri, Marcelo; Pasqualucci, Carlos Augusto

doi:10.1117/12.530315

Cited by 1 publication

(2 citation statements)

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“…In the medical field, Raman spectroscopy can be used to analyze and detect [158][159][160] nucleic acid substances and various tissues and fluids in the body and observe the possibility of lesions. SPR spectroscopy can diagnose and treat diseases through the detection of small molecules such as proteins and DNA in vivo.…”

Section: (19 Of 34)mentioning

confidence: 99%

“…Raman analysis SPR-Raman application Amount of components, additives, and pesticides [34,145] Composition, additives, and types of pesticides Allergen testing, additive analysis, pesticide residue testing Trace detection of drugs and explosives [146,147] Analysis of types of drugs and explosives [148][149][150][151][152] Public security inspection, driving under the influence drug detection, on-site analysis and investigation Quantity of matter, kinetic parameters [156,157] Structure and crystal form of medicines [153][154][155] Medicine manufacturing, screening, and new medicine development Small biological molecules such as protein and DNA Trace detection of heavy metal ions Film thickness, molecular dynamics Structures and types of nucleic acids and DNA [158][159][160] Types of heavy metal ions Microlattice, chemical bonding mode, and molecular structure [161][162][163][164] Early diagnosis and treatment of cancer and diabetes mellitus Environmental monitoring, pollution control, deep-sea exploration Observation of the chemical reaction process, bonding mode, molecular structure, and solution crystallization process www.advmatinterfaces.de…”

Section: Spr Analysismentioning

confidence: 99%

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Surface Plasmon Resonance (SPR) Combined Technology: A Powerful Tool for Investigating Interface Phenomena

Chen

Xin

Chang

et al. 2023

Adv Materials Inter

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Interface phenomena refer to the phenomena caused by various physical and chemical processes occurring at phase interfaces. These phenomena can include adhesion, friction, lubrication, evaporation, condensation, adsorption, monolayer formation, and other phenomena and are applied in many fields, such as food, papermaking, rubber, material science, energy, and biomedicine. However, traditional detection equipment cannot meet the interface phenomena observation needs because the information detected by techniques such as electrochemistry, spectroscopy, chromatography, and mass spectrometry is limited, as are the sensitivity and minimum detection limit. Surface plasmon resonance (SPR) combined technology is a powerful tool for investigating interface phenomena. This paper reviews all combination technologies of SPR with various conventional detection systems, emphasizing the combination with electrochemistry, Raman spectroscopy, and mass spectrometry. These technologies can observe interface phenomena through SPR and provide redox, molecular structure, functional group change, and other information. Through this information, the reactions on the interface can be made clearer and more controllable, which plays an important role in practical detection. In the future, SPR combined technology will mainly develop toward signal enhancement, light source coupling mode, and sensor chip design, and SPR will be combined with various detection technologies to achieve real‐time in situ detection of interface phenomena.

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Section: (19 Of 34)mentioning

confidence: 99%